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Weng JollyThe company name is only visible to registered members.A simple new vacuum Blood Collection Tubes test for allergy triggers
A simple new vacuum Blood Collection Tubes test for allergy triggers
There are at least three specific instances in which you may wish to incorporate IgE-specific testing into your practice and particularly in the pediatric patient with certain childhood diseases. IgE-specific testing can answer three questions: (1) Are the patient's symptoms caused by atopy? (2) Which allergens are responsible? (3) Where is the patient on the food/inhalant sensitization continuum, also known as the allergic march? Typical childhood diseases that may benefit from further studies include eczema, GI distress, recurrent acute otitis media, rhinitis, or asthma. If IgE-specific test results are negative, the symptoms are unlikely to have an underlying atopic basis and should be managed with symptomatic treatment. If IgEspecific test results are positive, other treatment alternatives become possible, along with allergen avoidance.
The final instance in which IgE testing may be considered is asthma in all its variations. Successful management of asthma commonly depends on distinguishing between allergic and nonallergic disease and accurately identifying a patient's symptom triggers. In allergic asthma, allergic sensitivities play a critical role in disease onset and severity. Patients commonly have a history of atopic disease, and their asthma exacerbations are triggered by environmental allergens. Some 60% of adult patients and up to 90% of children with asthma are estimated to have allergic asthma. Regardless of the different etiologies, these conditions share three common confounding symptoms: cough, wheezing, and dyspnea. Experts increasingly support the one airway theory, which holds that a common inflammatory process links upper and lower airways. In addition, more and more recommendations call for persons with asthma to be evaluated for signs and symptoms of persistent allergic rhinitis and vice versa. For the first time, IgE-specific testing is available in virtually every setting and can assist in definitive treatment with respect to the first step in allergy triggers and avoidance of those triggers.
Despite our increasing ability to accurately identify allergic triggers, patients likely will not be able to avoid all their allergens. The good news is they don't have to. They simply need to move below their allergic threshold (see Figure 1). Regardless of their allergic disease (ie, allergic rhinitis, asthma, eczema, etc.), few patients have a single allergic trigger. Instead patients have multiple triggers that “stack” up on one another until the individual reaches his or her allergic threshold and develops symptoms. By avoiding some or most of their triggers, patients may be able to slip below their allergic threshold so that their symptoms may largely disappear or at the very least become more easily managed.
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- 29 Jul 2009, 10:43 am
