Dr. Christoph Hartmann

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Dr. Christoph Hartmann

Dipl.-Inf.

Software-Entwickler

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Personal information

Professional experience (11 years, 3 months)

  • Jul 2009 - present

    (2 years, 11 months)

  • Mar 2008 - Jun 2009

    (1 year, 4 months)

  • Jan 2005 - Feb 2008

    (3 years, 2 months)

  • Jan 2002 - Dec 2004

    (3 years)

  • Mar 2001 - Dec 2001

    (10 months)

  • Employment status
    Employee

Educational background

  • Jan 2005 - Jul 2008
  • Oct 2000 - Nov 2004

About me

Publikationen
  • Welsch, C., Shimakami, T., Hartmann, C., Yang, Y., Domingues, F.S., Lengauer, T., Zeuzem, S., Lemon, S.M. Peptidomimetic Escape Mechanisms Arise via Genetic Diversity in the Ligand-Binding Site of the Hepatitis C Virus NS3/4A Serine Protease. Gastroenterology 142(3), 654-663, 2012. (Gastroenterology) (PubMed)
  • Hartmann, C., Antes, I., Lengauer, T.: Docking and scoring with alternative side-chain conformations. Proteins 74, 2009.(Proteins) (PubMed)
  • Antes, I., Hartmann, C., Lengauer, T.: Protein-ligand docking including protein flexibility: A hierarchical approach. From Computational Biophysics to Systems Biology, Proceedings of the NIC Workshop 2008.
  • Hartmann, C.: Modeling of flexible side chains for protein-ligand docking. Dissertation an der Universität des Saarlandes, 2008. (Dissertation) (Kolloquium)
  • Welsch, C., Domingues, F.S., Antes, I., Susser, S., Hartmann, C., Mayr, M., Albrecht, M., Sarrazin, C., Zeuzem, S., Lengauer, T. Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus. Genom Biology, 9(1): R16, 2008. (Genome Biology) (PubMed)
  • Hartmann, C.: IRECS – Prediction of side chain conformation ensembles, Poster auf dem Drug Discovery Workshop in Marburg, 2007. (Poster)
  • Hartmann, C., Antes, I., Lengauer, T. IRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models. Protein Science 16, 2007. (Protein Science) (PubMed) ( IRECS project page)
  • Lengauer, T., Hartmann, C.: Bioinformatics. In Comprehensive Medicinal Chemistry II, Volume 3: Drug Discovery Technologies, Elsevier: Oxford, 2006. (Elsevier)
  • Hartmann, C: Erweiterung der Dockingsoftware FlexE durch das Modell der Mean Field-Theorie. Diplomarbeit, Rheinische Friedrich-Wilhelms-Universität Bonn, 2004.(Diplomarbeit)

 

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