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• Rolando Rodriguez

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  "We know that cardiovascular disease is a major cause of death and disability in the developing world, but we are not doing enough to address it, " said committee chair Valentin Fuster, director, Mount Sinai Heart, Mount Sinai School of Medicine, New York City."If this challenge is not met, it will be impossible to achieve better health worldwide, " he added."Leaders in the field of cardiovascular health need to think and act more globally, and it is also incumbent upon the global health and development community to do more to confront cardiovascular disease and other chronic diseases. This is a problem that will require strong leadership at the highest levels."

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  Elevated ADMA - what are the therapeutic consequences? According to our increasing understanding of the pathophysiological role of ADMA for the development of cardiovascular diseases during the last years, this molecule has become a novel goal for therapeutic intervention. This is all the more true, as ADMA has been shown to induce endothelial dysfunction not only in patients with cardiovascular or metabolic disesases, but in the elderly in general.. The most obvious option to antagonize the deleterious effects of ADMA on the endothelium is dietary supplementation with L-arginine. ADMA competes with L-arginine for binding at the NO synthase, and the inhibitory action of ADMA on this enzyme`s activity can be reversed by L-arginine [8, 22, 77]. Thus, the ratio of the concentrations of L-arginine versus ADMA determines NO synthase activity, as depicted in Figures 2a and 2b. This means that elevated ADMA levels cause a relative, functional "L-arginine deficiency" even in the presence of L-arginine plasma levels within the normal range. Targeted dietary supplementation resulting in elevation of L-arginine`s plasma levels will normalize the L-arginine-to-ADMA ratio in the presence of high ADMA levels. Normally, sufficient provision of L-arginine cannot be maintained by modification of the usual Western diet alone in patients with "L-arginine deficiency diseases" (that are characterized by impaired NO-dependent vascular function). Regular intake of dietary L-arginine supplements is necessary in most patients to reach this therapeutic goal. Ref: www.allaboutadma.com ProArgi-9 Plus is Synergy's top selling product and the cornerstone of any nutritional regimen. One serving contains 5, 000 mg (5 grams) of elemental pharmaceutical grade L-arginine. Often referred to as the "miracle molecule, " L-arginine has potent health-enhancing properties. The remarkable properties of L-arginine were validated by the 1998 Nobel Prize in Medicine, and since then have created a frenzy of interest in the pharmaceutical and nutraceutical

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  If you are concerned about cardiovascular disease and/or or have one or more of the six risk factors identified by the American Heart Association*: such as diabetes, smoke or have smoked in the past, have high blood pressure, high cholesterol, have a family history of heart disease or are overweight, then it is important to understand the role of L-arginine, the main ingredient of ProArgi9+ in enhancing the bodies ability to increase the production of nitric oxide, critical for maintaining vascular health.

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  http://www.nutra-core.com/index.html www.ownyourhealth.mysynergy.net

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  Englisch (Fließend), Spanisch (Fließend)