Dr. Annalisa Macagno

• Supporting the development of business strategies through evaluation of technologies, due diligence investigations, analysis of market and competition, and scouting of strategic alliances • Supporting the design of business plans with analyses of value creation, definition of milestones, preparation of project plans and design of exit strategies

• Responsible for strategy development for new products (identifying new biomarkers, indications and technological platforms for new business opportunities in oncology). • Evaluating competitive positioning, developing market entry strategies and providing decision support to top management for business development and product launch. • Establishing biomarker plans, organising resources and managing portfolio of projects to qualify new biomarkers scientifically, technically and clinically.

• Led and managed portfolio of projects in oncology from biomarker selection to CE mark of IVD product. • Prepared and managed budget, reporting directly to CEO. • Led multi-disciplinary teams (research, regulatory, supply & manufacturing, clinical, medical affairs, commercial) for product development. • Supervised and coached the project team (3 direct reports), liaised KOL, managed external partners and CMOs. • Implemented compliance to regulatory requirement (ISO 13485) and managed risks.

• Analysed market opportunities and intellectual property landscape and supported management to define business strategies and project goals. • Integrated scientific research project proposal into a cost effective business plan for the preclinical development of a novel vaccine candidate for HSV. • Provided advise for the development of a preclinical cytomegalovirus vaccine candidate out-licensed to Pfizer and contributed to the creation of a proprietary technology platform for the design of vaccines.

• Set up company’s activities from inception until full capacity business, supporting the board to define goals and select projects (autoimmunity/inflammation). • Planned, managed and directed execution of all projects (budget, monitoring of prpogress to reach milestones). • Coordinated a cross-functional team of 30 experts (13 scientists and group leaders, 5 direct reports) at 6 international locations for advancing 4 programs to full pre-clinical characterization.

• Provided input in cancer immunobiology • Managed an oncology project and supervised the antibody technology team for the development of 8 lead antibodies for use in passive therapy or in combination with vaccine (subject of patent application WO 2012 / 163771). • Doubled the efficiency of cell technology and improved its robustness by successfully establishing quality assurance procedures. Cut down to 1/3 the time required for molecular cloning and complete sequence identification.

Biochemistry / Immunology

Biomolecular orientation, Biochemistry