Dr. Marco Natali

• Assessed the pathogen safety risk for patients due to Quality Events and the use of Raw Materials in product manufacturing • Evaluated the pathogen testing strategy, supporting the transition from in vivo assays to Next Generation Sequencing • Improved the visibility and impact of the team within the global organization to ensure product safety • Presented data-driven analyses and documentation contributing to decision-making in support of business needs

Personalized tutoring in Mathematics, Chemistry, and Biology for pupils and medical students in Switzerland

• Responsibility of NCs/CAPAs (investigations, root cause analysis, and documentation), SOPs, WIs and protocols • Diagnostic laboratory processes (clean room, pipetting robots, results interpretation) in the framework of the pandemic heavy workload, Process optimisation by development of methods to identify and reduce contamination • Team supervision during shift work, transfer of technical knowledge, and training of coworkers • Completed a course in Project Management

• Purified pharma grade phytochemicals under cGMP. Improved production processes and the related GMP documentation • Planned the realization of a potential Microbiology Department, integrating equipment needs with safety and quality protocols • Acquired technical expertise about HPLC, Crystallization, Distillation, Extraction by Supercritical CO2

• Laboratory management and supervision of students • Drug discovery (planning of synergistic pharmacological treatments, cell-based assays, human cell cultures) • Pre-clinical research (planning, execution, analysis, interpretation, and presentation of results) • Scientific writing (reports, articles, congress posters, dissertation)

In vivo studies in the laboratory of Prof. András Simon about neural regeneration in salamander's mesencephalon. Expertise: stereotaxic brain surgery in newts; RNA probe preparation and in situ hybridisation; image handling for quantitative analysis; tissue harvesting and slices preparation; immunohystochemical staining. Supervisor: Dr. Matthew Kirkham. Research group: Prof. András Simon.

Expertise: immunohystochemical staining; microinjection in planarian worm; hystological preparation of slices and whole mount; biomolecular techniques. Supervisor: Dr. Maria Emilia Isolani. Research group: Prof. Renata Batistoni.

In vitro chemo-physical approach studies in the laboratory of Prof. Ferdinando Secco about the intercalation of alkaloid Coraline into Nucleic acids. Expertise: absorbance and emission measurements; spectrofluorimetric titrations; kynetic perturbation by T-jump. Supervisor: Prof. Tarita Biver. Research group: Prof. Ferdinando Secco.

Cell Proliferation, Biomaterials, Drug discovery, Cancer, Wound Healing

Cell Proliferation, Stem Cells, Regenerative Medicine, Cancer

Biotechnologies