Noémie Kunkler

Root Cause Investigation under CAPA Feasibility and verification test of hardware and software changes. Work in biosafety laboratories type 1 and 2 on cobas® 68/8800, 4800, and CAP/CTM. Organization, implementation, and support of testing activities on Diagnostic devices. Implementation of performance and integration tests. Monitor and report of errors, problems, and improvements. Create test cases and documentation of test results. Create reports, reviews, and updates of documents.

Product Care team Organisation, implementation, and support of testing activities on Diagnostic devices. Implementation of performance and integration tests. Monitoring and reporting of errors, problems, and improvement. Creation of test cases and documentation of test results.

. Factors limiting the room temperature stability of nucleic acid amplification reagents. I investigated the effect of diverse additives (solvents, magnesium…) on the dNTPs in aqueous solution using accelerated testing at elevated temperatures. I also followed the activity of master mixes by qPCR or LAMP to check their stability at different temperatures.

Microbiological analysis of food products. I did the preparation of the culture media, recorded all the data on the analysis in the software LIMS (Laboratory information Management System) to ensure the traceability. I monitored the cleanliness of the employees, the machinery, as well as the micro-organisms in the air of the laboratory.

Microbiological analysis of food products. I did the preparation of the culture media, recorded all the data on the analysis in the software LIMS (Laboratory information Management System) to ensure the traceability. I monitored the cleanliness of the employees, the machinery, as well as the micro-organisms in the air of the laboratory.

The consequences of a mutation in dynein on mitochondria: study on fibroblasts on primary culture. Techniques used: cell culture, Western Blot, PCR, qPCR, immunolabelling, extraction-purification of mitochondrial DNA, protein dosage, genotyping.

Clarification of protocols in order to evaluate cellular viability. Techniques used: cell culture of PC12 and of Hepatocyte. I assessed cell viability with MTS, Trypan Blue and Hoechst.

Biology and plant development: Molecular biology and biotechnology in plants