Dr. Ann-Christin Hau

Next Generation Sequencing (DNA & RNA), array-CGH (Agilent), Patient-derived Xenografts (PDX), Glioblastoma multiforme, Low-grade Gliomas, IDH1-Mutation, Methylation Analysis

fellow of the Ludwig-Edinger Stiftung in Frankfurt am Main

successful participation in a bioinformatics training at the University Belfast organized by COST (European Cooperation in Science and Technology: Alexander Thompson, Miguel Torres, Beatrice Ferreira) ; contents: - sequence searching, alignments, next generation sequencing (Illumina), SNP analysis, microarray data analysis and epigenomics, introduction to R2 systems biology approaches and pathway analysis, miRNA/siRNA tools and ressources, protein ressources and tools

Housing, rearing and nutrition of the internal stock collection Drosophila melanogaster

Instruction of undergraduate biology student teachers in the following techniques: - practical exercise in the Mendelian laws, e.g. sex-linked patterns of inheritance, gene-localisation methods, lethal-factors, etc. molecular cloning, Southern-Blot and restriction mapping; Model organism: Drosophila melanogaster

Instruction of biology graduate students in the following techniques: - In-Situ hybridization, plasmid-rescue method, enhancer-trap, phenotype analysis, preparation of Drosophila polytene chromosomes and imaginal discs, immunostainings, BrdU cell proliferation assays; Model organism: Drosophila melanogaster

Scientific, practical year abroad with the Erasmus academic exchange service; Max F. Perutz Laboratories, Group Prof. Wiche, Developmental Biology & Disease Mechanisms, Molecular cell biology, scientific studies on various cytolinker proteins involving the following techniques: - Isolation, cultivation, transfection and live-cell imaging of primary murine fibroblasts, molecular cloning, immunostainings, - Bio-chemical analyses: Western-Blot, Coomassie, silver-stainings, Pull-downs

Neural stem cells, Viral manipulation, Mouse Genetics

Neurobiology, classical and developmental genetics in drosophila melanogaster, physiological chemistry and patho-biochemistry