Aurélia Lappert

Formulation representative in a multidisciplinary project team (analytics, chemists, biopharmaceutics) accountable for the development of DP for chemical entities for the supply of non-clinical and clinical studies. Leading since 2 years an age appropriate medicines initiative with the main objective to provide guidance to better design and develop appropriate medicines for specific populations from pediatrics to geriatrics.

Development of new drug product (solid dosage form and transdermal drug delivery system (patches). Management and supervision of DP related development aspects (formulation and process development, development strategy, documentation, budget and project management). Management and coordination of tech transfer activities with external partners Ensure delivery of Clinical Trial Material on time. Ensure good and efficient collaboration and communication with other functional areas and CMO

Development of pharmaceutical formulations and processes, especially in Transdermal delivery system (patches). Support and supervison of the technical staff within the formulation team. Improvement of physical properties of patches and development of new manufacturing process. Supervision and performance of rheological measurements. Organisation of clinical material for clinical study. Support of qualification and validation activities. Coordination and participation to manufacturing at the CMO.

Development of microemulsion containing hydrophobics ingredients, especially vitamins. Choice of surfactants, carrier oil, active ingredients Process development Quantification of oil encapsulated with HPLC measurements Contact with surfactants manufacturers

Improvement of the bulk property of an oil dispersion herbicides formulation. Project surpervised by Ms Smita PATEL, Lab Leader in the formulation department of BCS. - Learned about the theoretical concepts of rheological measurements, optimization of emulsion properties (dispersion in water stability) by choosing surfactants, polymers and additives. - Conducted research to find new additives to improve the bulk properties of the dispersion - Manufactured formulations, carried out rheological measurement

solid formulations, use of polymers in formulation, Rheology, encapsulation, product for crop protection, antifoam, concrete additives, determination of a formulation composition. Initiation to the formulation technologies in cosmetic, polymerisation engineering and biology.