Marcelina Szczygiel

Graduate student of Medicinal Chemistry

Bis 2021, Research Intern, Oklahoma Medical Research Fundation

Wrocław, Polen

Über mich

I am a master student at the Wroclaw University of Science and Technology and I expect to defend my master thesis in September. This June I have finished a research project at the Oklahoma Medical Research Foundation under the direction of Dr. Benjamin Miller, as a Fulbright scholar. My studies were based on work with inducible cell-specific mouse models in order to determine changes of protein turnover with aging and investigation proteostasis maintenance with treatments that slow the aging. I have broad experience in enzymology, genetic engineering (including PCR) techniques as well as in techniques of purification and analysis of chemical compounds. Handling stress, and additionally the ability to divide attention, helps me in multitasking, which features me at my laboratory work. I am a person who enjoys challenges and I am open to new opportunities. Personally, I am an enthusiastic and sociable person, and I am able to work both in a team as well as using my own initiative.

Fähigkeiten und Kenntnisse

Cell Biology
Organic Chemistry
Cell culture
LCMS
GC-MS analysis
HPLC
PCR
ELISA
Western Blot
INTACT
TRAP
Animal handling
IP injection
Animal Science
Preparation tissue for proteomics
Electrophoresis
Organic Synthesis
UV / Vis spectroscopy
Protein

Werdegang

Berufserfahrung von Marcelina Szczygiel

  • 10 Monate, Sep. 2020 - Juni 2021

    Research Intern

    Oklahoma Medical Research Fundation

    Inducible cell-specific mouse models for determination of changes in protein turnover rate with aging, and investigation of the mechanisms of proteostasis maintenance with treatments that slow the aging process.

  • 9 Monate, Feb. 2019 - Okt. 2019

    Researcher

    Wroclaw University of Science and Technology

    Human Neutrophil Elastase proteolytic activity in cancer cell lines using activity-based probes.

  • 1 Monat, Sep. 2019 - Sep. 2019

    Intern

    Institute of Immunology and Experimental Therapy Polish Academy of Sciences

    Amplification of bacteriophages in gram-negative bacteria and evaluation of crude bacteriophage lysates.

  • 1 Monat, Juni 2018 - Juni 2018

    Intern

    Institute of Immunology and Experimental Therapy Polish Academy of Sciences

    Structural investigation of cell surface-derived bacterial proteins isolated from various Bifidobacterium longum strains and their immunomodulatory properties on different human and mice cell lines.

Ausbildung von Marcelina Szczygiel

  • Bis heute 5 Jahre und 4 Monate, seit Feb. 2019

    Medicinal Chemistry

    Wroclaw University of Science and Technology

    Master Thesis project involved: - Synthesis of innovative quenched activity-based probes with a high affinity towards hNE; - Catalytic preferences studies of qABP towards hNE enzyme; - Murine progenitor cells' differentiation to neutrophils and visualization with qABP by inverted fluorescent microscope application.

  • 3 Jahre und 4 Monate, Okt. 2015 - Jan. 2019

    Biotechnology

    Wroclaw University of Science and Technology

    The subject of the thesis was “Crimean-Congo hemorrhagic fever virus – structure and disease aetiology.”

Sprachen

  • Englisch

    Fließend

  • Deutsch

    Grundlagen

Interessen

Yoga
Hiking
Traveling and immersing myself in other cultures
Baking
Books

21 Mio. XING Mitglieder, von A bis Z