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The Position

Within "Synthetic Molecules Technical Development” the Process Analytical Technology (PAT) group is responsible for the implementation of PAT tools to support a fast and effective drug substance and drug product process development of our pipeline projects. We are also developing and validating PAT procedures for Real Time Release Testing (RTRT) and support novel technology platforms with dedicated PAT solutions.

In our pursuit of novel technology, we have identified Terahertz spectroscopy as a promising PAT tool to correlate with tablet dissolution parameters. The primary objective of this project is to demonstrate the feasibility of this technology for implementing RTRT in tablet dissolution. This internship offers an opportunity to work with Terahertz technology and includes performing laboratory activities such as tablet disintegration, dissolution testing, and other tablet evaluations.

As an intern you will support both the PAT and Analytical Research & Development (ARD) department in evaluating the potential of this technology.

The Opportunity:

• Review of the relevant literature applicable to the project

• Training in relevant SOPs (Standard Operating Procedures) and analytical equipment

• Terahertz measurements of the selected formulations

• Disintegration/Dissolution testing of oral solid dosage forms (tablets) and correlation with the Terahertz data

• Regular discussion of project progress with supervisors and planning of next steps

• Writing of final report

Who you are:

You are a student (or you graduated within 12 months prior to the start date) preferably in the subject of Pharmaceutical Sciences, Pharmaceutical Technology, Chemistry or Chemical Engineering and have an interest in technical and analytical issues. Furthermore, you are interested in using and sharing your knowledge as part of your Internship in a modern working environment. Your further profile for this position:

• Reliable and accurate working style in a non-GMP environment

• Team-oriented and decision-making personality

• Self-sufficient, problem solving-oriented work habits

• Good knowledge of MS-Office (Word, Excel, PowerPoint)

• Hands-on laboratory experience, specifically in performing spectroscopic measurements.

• Data & modeling skills (e.g. chemometric modeling, multivariate data analysis)

• Matlab/Python/R/C++ programming skills &; high affinity to digital tools

• Proficiency in English and German is a plus

This internship opportunity is one of a number of positions we offer in the department per semester and is not suitable for writing a Bachelor/Master/Diploma thesis.

The interviews will take place on an interview day with all considered candidates and the whole department.

Your complete application includes the following documents

• A Current CV and a Motivation Letter

• A certificate of enrollment (if you are currently studying)

• For Non-EU/EFTA citizens: Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies and you must be enrolled during the entire duration of the internship

• The RiSM task (see below)

Application Process

The application deadline is 24.08.2025. All successful final candidates will be invited to a virtual interview day which will take place on 15.10.2025.

The Internship will ideally start in April 2026 for 6-9 months, please indicate your preferred start date and duration in your application.

More information about the Roche Internship program in Synthetic Molecules (RiSM) and other opportunities within this program you can find here .

Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities.

RiSM task

Artificial intelligence (AI) is rapidly transforming various aspects of life. Its applications span from ubiquitous uses such as virtual assistants and recommendation systems to complex domains including healthcare and scientific research. Assume that you are writing your own grant application for a 12-months internship that leverages AI within your chosen field of study or in a domain relevant to your academic background. We anticipate receiving your proposal (maximum of 3 slides, PDF format) alongside your application.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.