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The Position

Chronic kidney disease (CKD) is a major health issue affecting approximately 850 million people worldwide. Current treatments for CKD primarily focus on slowing the disease’s progression; however, many patients eventually progress to end-stage renal disease, where the only option is kidney replacement therapy. Studying CKD in vitro has been challenging due to the lack of robust model systems that accurately replicate the disease’s complexity.

Our Cardio-Metabolic & Immunology department (CMI) is working on kidney organoids derived from induced pluripotent stem cells (iPSCs) to recreate kidney function in health, disease and drug response. Ultimately, the goal is to build an innovative human model system for integration at key stages of our Discovery Nephrology pipeline.

The Opportunity

In this role, you will work in close collaboration with CMI and pRED scientists and you will…

• Generate a scalable source of iPSC-derived kidney organoids.

• Establish culture conditions for kidney disease modeling and drug response.

• Perform phenotypic and molecular characterization of organoids utilizing cutting edge technologies.

• Contribute to a scientific publication.

Who You Are

• You hold a Bachelor degree in Biological Sciences (or related field), and are currently enrolled in an M. Sc. program or have completed one in the past 12 months.

• You have hands-on experience in cell culture methods and a strong interest in human complex model systems.

• You are an excellent communicator in English, both verbally and in writing.

Additional Information

• This is a 12-month internship based in Basel, Switzerland.

• Please upload a current CV along with your enrollment certificate and/or a copy of your degree(s).

• For Non-EU/EFTA citizens: Due to regulations, you must provide a letter from your university confirming that an internship is mandatory for your studies and specifying the required length of the internship. Please upload this letter, along with your enrollment certificate, CV, and cover letter.

Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity!

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.