Start date as soon as possible. The position is subject to the German Academic Fixed-Term Contract Act (WissZeitVG, Section 2 (2)) and is initially limited to two years until the end of the project.

The Institute of Molecular Medicine II, headed by Prof. Dr. Philipp Lang, focuses on the molecular basis of infections and immune responses and the development of new therapeutic options in connection with antitumor immune responses. This involves immune mechanisms during chronic viral infections and tumor growth, including innate and adaptive immunity. A central focus lies in understanding immune dysfunctions associated with these diseases.

Our goal is to elucidate how chronic viral infections develop and to identify mechanisms that drive tumor growth, thereby contributing to the development of novel therapeutic strategies within a basic research framework. The Institute of Molecular Medicine II is actively involved in several research networks dedicated to these topics and applies a translational approach across its individual research projects.

The current research project will focus on improving immunotherapy regimens. Specifically, several immunotherapy model systems will be applied in preclinical murine models (e.g.: CAR-T, Virotherapy, BiTEs). We aim to use small DNA molecules to cleave target sequences and thereby improve anti tumor immunity. Experience in immunology, tumor biology, molecular biology, and delivery/lipid nanoparticles combined with enthusiasm about experimental science in an international team is desired.

Your tasks
• Coordination, organization, and scientific implementation of the research project
• Development of new scientific research areas and publication of research results in the form of articles in journals
• Administration of project- and laboratory-related applications, as well as laboratory animal management

Your profile
• University degree in medicine, biology, biomedicine, or related fields
• Doctorate or Ph.D. related to the advertised areas of responsibility
• Comprehensive experience in immunological and molecular biology in vivo and in vitro techniques
• Profound knowledge of murine animal models
• Successful publication of articles in renowned scientific journals is desirable
• High motivation, dedication, and a passion for making a difference through basic research

In addition, we are looking for
• Interest in translational immunological research
• Ability to work on complex problems in a structured and solution-oriented manner
• Friendly and situation-appropriate communication skills, as well as strong teamwork skills
• Excellent leadership qualities
• Very good verbal and written communication skills in English and preferably also in German

We offer:
We offer you the opportunity to work in a highly motivated, international team on an exciting research project with great translational potential in the field of immuno-oncology. You can expect modern laboratories and access to state-of-the-art technologies.
• Experience with translational projects in immune-oncology
• Highly motivated international team
• Enthusiastic research project with translational potential
• Individual career opportunities based on qualification
• Fully renovated lab space including state of the art equipment
• Access to state of the art facilities including transcriptomics and proteomics
The employment contract will be concluded with Heinrich Heine University Düsseldorf.

Remuneration will be based on TV-L in pay grade 13, taking into account all previous periods of service.

Heinrich Heine University Düsseldorf is committed to increase the proportion of women in its workforce. Applications from women will be prioritized if they demonstrate similar qualifications, skills, and performance unless there are overriding reasons related to another candidate. We specifically encourage applications from qualified severely disabled individuals and equivalent persons under SGB IX. Part-time employment is possible.

By submitting your application documents, you agree that they become the property of Düsseldorf University Hospital and will not be returned for cost reasons.

If you have any questions regarding the job profile, please contact Dr. Witkowski (email: admin_lang@uni-duesseldorf.de; tel. 0211-81 14532).

Please submit your application, including your CV, transcripts of records, a statement of research experience and interests, your expected availability date, and references within two weeks of the publication of this advertisement. Applications should be sent, preferably by email as a single PDF file, to the following address:

admin_lang@uni-duesseldorf.de oder

D 01.2.1 – Kennziffer: 562E/25