PhD Researcher (f/m/x): Studying the metabolic interaction within a microbiome model system, focusing on the role of transporters

Place of work

Working time

Contract limitations

Salary

Contact

Your contact for any questions you may have about the job:
Prof. Dr. Martin von Bergen
martin.vonbergen@ufz.de

Your application

Please submit your application via our online portal with your cover letter, CV (please omit your photo, age, or marital status) and relevant attachments.

Diversity and Inclusion

The UFZ has a strong commitment to diversity and actively supports equal opportunities for all employees regardless of their origin, religion, ideology, disability, age or sexual identity.
We look forward to applications from people who are open-minded and enjoy working in diverse teams.

Your tasks

• You will cultivate the simplified human gut microbiome model (SIHUMIx) in a continuous culture and analyse the species-specific secretion and uptake of metabolites by mass-spectrometry-based metabolomics.
• You will detect the presence of transporters and metabolic enzymes by mass-spectrometry-based metaproteomics and meta-transcriptomics, and integrate multi-omics information to detect associations between metabolism and transporter abundance.
• You will develop mutants and CRISPR/Cas approaches to validate the interdependency of metabolic pathways and transporters in the SIHUMIx consortium.
• You will cooperate with our partner in the project to validate genome-based metabolic models. You present results at international conferences and prepare publications in peer-reviewed scientific journals.
• You present results at international conferences and prepare publications in peer-reviewed scientific journals.

We offer

• Excellent supervision and optimal professional and interdisciplinary qualification through our HIGRADE graduate programme
• The freedom to master even the most demanding challenges between basic research and practical application
• The opportunity to work in interdisciplinary, international teams and benefit from a wide range of perspectives
• Firstclass integration into national and international research networks to work together on global challenges
• Excellent research infrastructure and research data management to optimally support your work
• A wide range of options for balancing care responsibilities and work through our family office
• Competent support and advice for international colleagues arriving at the UFZ from the ‘International Office’
• Special annual payment, capital-forming benefits and subsidised Deutschland-Job-Ticket
• A workplace in a vibrant region with a high life quality and social and cultural diversity

Your profile

• Master's, Diploma or equivalent degree in biological or biochemistry, or related areas
• Experience in analytical chemistry
• Skills in bioinformatics with a focus on statistical tools for analysing omics data
• Motivation to work in an interdisciplinary team or similar
• Proficiency in scientific English (written and spoken)
• Willingness to cooperate on metabolic modelling with colleagues in the group of Christoph Kaleta in Kiel

• Academic Qualification: The applicant must hold a relevant master’s degree or equivalent and must have obtained the degree or equivalent by the DC start date
• To be recruited to the network as a doctoral candidate, applicants must not already be in possession of a doctoral degree (i.e. a Ph.D. degree)