“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

At the earliest date possible, the DKTK partner site Frankfurt/Mainz — Department of Hematology and Medical Oncology at the University Medical Center Mainz is looking for a Technician (BTA/MTA) for the DKTK research project "ASTRON" in Part Time (19,75 h/week).

Reference number: 2025-0190

At the DKTK partner site Frankfurt/Mainz (work location Department of Hematology and Medical Oncology at the University Medical Center Mainz), an MTA/TA is sought for the DKTK research project “ASTRON”. The main task is to carry out experiments (in vitro and 3D bioprints) based on next-generation cellular interventions that can work synergistically with mRNA intervention. The candidate will separately develop interventions and test these in conjunction with mRNA patterns.

The main activities include:

• Cell culture (immune cells, tumor cell lines, but also tissue explants from fresh, healthy or cancer patients, microscopy analysis)
• CAR/TCR-engineering T cells
• mRNA interventions within the tumor microenvironment
• DNA and mRNA preparation, PCR, Western Blotting
• Functional testing (tumor cell targeting and killing by CAR/TCR-equipped T cells, analysis of T cell metabolic fitness etc.)
• In vivo oncology/PDX models (mouse studies)
• Maintenance of in vitro cell lines
• Administration and documentation (assist with analysis of data, the preparation of research publications and reports, conduct literature searches, and also order lab supplies)
• Assist in designing and planning research project-related experiments with the group leader
• Performing laboratory-based research with the requirements of good laboratory practice using a range of techniques, including in immunology, cellular biology, biochemistry and lately in vivo mouse studies

• BTA, MTA or equivalent
• Prior experience with cell culture and in molecular biology and biochemistry methods
• Team spirit
• Good German and English communication skills

• Excellent framework conditions: state-of-the-art equipment and oppor­tunities for inter­national networking at the highest level
• 30 days of vacation per year
• Flexible working hours
• Remuneration according to TV-L incl. occupational pension plan and capital-forming payments
• Possibility of part-time work
• Family-friendly working environ­ment
• Sustainable travel to work: subsidized Germany job ticket
• Unleash your full potential: targeted offers for your personal development to further develop your talents 
• Our Corporate Health Manage­ment Program offers a holistic approach to your well-being

Tobias Emmerich
Telefon: +49 6221 42-1653

The position is limited to 2 years.

Application Deadline: 05.08.2025

Are you interested?
Then become part of the DKFZ and join us in contributing to a life without cancer!

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Deutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | www.dkfz.de