At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.

Associate Principal Scientist - Biology & Assays (all genders)

As an Associate Principal Scientist Biology & Assays (all genders), you will work on innovative drug discovery projects and be an active member of highly interdisciplinary and cross-organizational research teams. With your expertise in biochemistry and cell biology, you will develop and implement tailored assay systems for data-driven decision-making. You will analyze key scientific questions in projects, create strategies and assays to link targets and modalities, and contribute to solving complex biological questions. Thanks to your experience and strategic thinking, you will make a crucial contribution to advancing research – driving medical progress and serving patients.

YOUR TASKS AND RESPONSIBILITIES

• Focus on drug discovery projects and be an active member of highly interdisciplinary and cross-organizational teams
• Using your expertise in protein biology, develop strategies to understand the links between targets and modalities, identify tailored lead finding approaches and develop relevant assay systems to probe target biology
• Biochemical assay development for enzymes, protein-protein interaction and protein degradation
• Establishment of novel enzymatic readout cascades, analysis of enzyme kinetics and study of biophysical drug/protein interaction
• Identify druggable entry points and relevant MoAs and establish biochemical assays in high throughput formats (e.g. TR-FRET, FP)
• Performing High Throughput Screens with robotic systems
• Critically assess key scientific questions in projects and develop and execute fit-to-purpose biological assays for data driven decision making
• Seamlessly collaborate with disease biologists, modality experts, drug discovery scientists and computational biologists to develop state-of-the-art methods and techniques to answer complex biological questions
• Keep up to date with the latest advances in assay development and drug discovery technologies by scouting innovation opportunities with external partners
• Engage with the broader scientific community through publications and conference presentations
• Supervise and mentor lab associates, interns and postdocs to drive scientific projects

WHO YOU ARE

We are excited about your talent and passion for this position. Attracting the right talent is important to us. We would be happy to work with you to identify and create the career and development opportunities you are looking for. And if you don't meet all the requirements, we still look forward to receiving your application. We are all constantly learning!

• PhD degree in Biochemistry or equivalent with post-graduate training in an industrial or academic environment
• Expertise in biochemical assay development, and its application to complex biological problems in drug discovery
• Deep knowledge of enzymology, enzyme kinetics, protein/protein interaction assays
• Experience in protein expression and production in eukaryotic, insect and bacterial cells
• Experience with a variety of biophysical methods like SPR, TSA, MS or MST
• Knowledge of structural biology: x-ray, cryoEM, alphafold, molecular modelling is a plus
• Hands on experience with protein biology, structural biology, molecular biology and lab automation.
• Broad knowledge of modalities available to address different targets
• Digital literate – ability to use digital analysis tools and to effortlessly communicate with computational biologists and data scientists
• Strategic thinker with a strong interest for drug discovery, driven by the purpose of helping patients in need
• Fluent in English with excellent verbal, written communication and interpersonal skills to work across functions and within external collaborations

ADDITIONAL INFORMATION

This is a fixed-term contract for 24 months.

WHAT WE OFFER

Our benefits package is flexible, appreciative, and tailored to your lifestyle, because: What matters to you, matters to us!

• We ensure your financial stability through a competitive compensation package, consisting of an attractive base pay and our annual bonus. In addition, managers can recognize special contributions by granting an individual performance award.
• Whether it’s hybrid work models or part-time arrangements: Whenever it is possible, you will have the flexibility to work how, when and where it is best for you.
• Your family is a top priority. We offer loving company daycare centers at multiple locations, support in finding childcare, time off for the care of elderly or dependent family members, summer camps for children, and much more.
• We support your professional growth by providing access to learning and development opportunities, training programs through the Bayer Learning Academy, development dialogues, as well as coaching and mentoring programs.
• We support your health and well-being with free check-ups by our company doctor, health seminars, and a wide range of initiatives that promote a healthy lifestyle.
• We emb diversity by providing an inclusive work environment in which you are welcomed, supported, and encouraged to bring your whole self to work.

Be You. Be Bayer.

#LI-AMSEMEA

YOUR APPLICATION

This is your opportunity to tackle the world’s biggest challenges with us: Maintaining our health, feeding growing populations and slowing the rate of climate change. You have a voice, ideas and perspectives and we want to hear them. Because our success begins with you. Be part of something big. Be Bayer.

Bayer welcomes applications from all individuals, regardless of national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, orientation, gender identity, gender expression or any criterion under applicable law. We are committed to treating all applicants fairly and avoiding

Location: ​​ ​ Germany : North Rhine Westfalia : Wuppertal-Aprath​

​​Division: ​ Pharmaceuticals​

Reference Code: 849654​

#Jobdrehscheibe

Bereitgestellt in Kooperation mit der Bundesagentur für Arbeit.