Dr. Katja Schneider

Persönliche Referentin der Institutsdirektion (bis 2017 Prof. Sabina Jeschke, jetzt Vorstand DB), Feb-Jul 2018 Büroleitung Public Relations. Das IMA: Lehrstuhl für Informationsmanagement im Maschinenbau und IfU: An-Institut für Unternehmenskybernetik e.V. forschen u.a. zu Industry 4.0, künstlicher Intelligenz, Logistik und Kybernetik.

Generation of a high-quality test platform in BY-2 tobacco cells for an industrial partner Dow AgroSciences. We developed a system to test the quality of insertion events mediated by zinc-finger-nucleases (similar to CRISPR/Cas) and confirmed seamless integration of large DNA fragments. I was responsible for method optimization, data analysis and project management.

The Agroprotect GmbH employed a patented discovery to use antibody fragments coupled to antifungal peptides to develop fungal-resistant plants. I was responsible for project design and laboratory management to identify and analyse plant candidates to bring to market. Agroprotect GmbH is a spin-off from Frauhnhofer IME in Aachen.

1) Characterization of an acyltransferase in brassinosteroid-metabolism (Arabidopsis thaliana): mutant plant phenotypic analysis, in vitro enzyme assay for substrate identification 2) Chemical genetics screen for the identification of modulators of cell and organ size: flow cytometry 3) biochemical characterization of a SUMO E3 ligase involved in regulation of cell cycle: Western blotting, protein production for antibody generation, yeast complementation assay Publication: Ishida et al., Plant Cell, 2009

Establishment of a yeast three hybrid screen for the identification of binding proteins for small molecules (plant hormones): generation of a cDNA library from wounded Arabidopsis leaves, establishment of the yeast system, candidate screening Publication: Schneider et al., Curr. Topics Phytochem., 2008 (Review)

Zielgerichtetes Management durch systemisches Handeln, strukturierte Steuerung und eine exzellente wissenschaftliche Basis. Analytisches und kreatives Denken auch in fachfremden Bereichen, mit einem Auge für Details und die menschliche Seite.

1) Rational design of enzyme substrate usage: cloning and heterologous expression of enzyme variants based on 3D models 2) Identification of substrates for an enzyme family based on data from project 1: diverse enzyme activity assays Schneider et al., PNAS, 2003, de Azevedo Souza, Plant Cell 2009