Dr. Markus Krupp

Angestellt, Applications-Manager Signal Detection, Merck Group

Mainz, Germany


PV Signal Managment
Drug Safety
Next Generation Sequencing
Big Data
Personalisierte Medizin
High Performance Computing
Data Scientist
Ausgeprägte kommunikative Kompetenzen
Verschiedene Programmiersprachen wie C++ R oder Py


Professional experience for Markus Krupp

  • Current 9 years, since Jan 2015

    Applications-Manager Signal Detection

    Merck Group

    Management of signaling systems within the adverse event database of Global Drug Safety, compliant with FDA Good Pharmacovigilance Practices, ICH topics, and EU GvP Module IX Signal Management. Providing qualitative and quantitative periodic safety outputs using disproportionality analysis of company products VS MedDRA terms based on MGPS and PRR. Interfacing medical and technical departments to harmonize mutual understanding and efficient collaboration to provide PSUR and RMP reference data.

  • 3 years and 7 months, Mar 2012 - Sep 2015

    Bioinformatician, Biomedical expert, Data scientist

    Johannes Gutenberg-Universität Mainz
  • 7 years, Mar 2005 - Feb 2012

    Bioinformatician, biomedical experts, Computational Scientist

    Universitätsmedizin der Johannes Gutenberg-Universität Mainz

    - Systems management & administration, including Cluster, Database- & Web-Server - Several biomedical & bioinformatics projects, highlighted projects: -- Analyzing gene expression data (Microarray & Generation Sequencing) in order to develop a functional compendium on serious diseases. -- Analysis of genetic time series profiles of liver transplanted patients to reveal genetic markers predicting the patients benefit of liver transplantation. -- The generation of a functional cancer map

  • 9 months, Jun 2004 - Feb 2005


    European Molecular Biology Laboratory

    Diploma thesis: “Integration of biological databases and application to environmental genomics”: - Integration of KEGG: 'the Kyoto Encyclopedia of Genes and Genomes' into STRING: 'Search Tool for the Retrieval Interacting Genes/Proteins' - Application of pathway data to environmental genomics

  • 8 months, Oct 2003 - May 2004


    Merck KGaA

    Student research project: “Merck Pathway Database: design and implementation“: - Designing a schema and implement a Merck pathway database (MPD) to facilitate pathway data integration and analysis - Benchmarking the quality of the MPD with respect to TransPath

Educational background for Markus Krupp

  • 1 year and 4 months, May 2013 - Aug 2014

    Bioinformatics, biomedicine

    Johannes Gutenberg-University Mainz

  • 2010 - 2012


    Johannes Gutenberg-University Mainz

  • 2001 - 2005


    University of applied science Bingen


  • English


  • German

    First language

  • French


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