Postdoc position (d/f/m) developing gene editing therapies for ANO5-related muscular dystrophy

Work time

Salary group

Working at Charité

We invite applications for a highly talented postdoctoral researcher to join the Muscle Research Unit with Outpatient Clinic for Muscle Disorders at the Experimental and Clinical Research Center (ECRC) in Berlin, Germany. The ECRC is part of the largest university hospital in Europe – the Charité – Universitätsmedizin Berlin – and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC).

Our lab is developing gene and cell therapies for muscle wasting disorders. We combine stem cell research, CRISPR technologies, novel humanized mouse models of neuromuscular disorders and state-of-the-art delivery technologies for nucleic acid therapeutics, as well as research on disease mechanisms (see our publications here . Our team is at the forefront of bringing autologous cell replacement therapies with CRISPR-edited muscle stem cells towards the clinic ( https://www.mdc-berlin.de/news/news/deep-expertise-and-bold-vision-myopax-launches-berlin ).

The Charité and Max Delbrück Center provide access to a vibrant scientific environment, cutting-edge infrastructure and great opportunities for collaborations and postdoctoral training.

Overview of the position

• The advertised position focuses on developing gene editing therapies for Anoctamin 5 (ANO5)-related muscular dystrophy
• You will conduct independent and collaborative research of high international quality within the project’s scope
• You will be employed as a research associate: According to §110 (4), sentence 3 of the BerlHG, research staff are entitled to an appropriate amount of time during working hours for their own scientific further qualification

What we are looking for

• PhD in life/natural sciences (cell biology, molecular biology, genetics or related field)
• Fluent in English, written and spoken
• Strong motivation to produce excellent science with a translational focus
• Good organizational skills
• Experience in stem cell research, skeletal muscle biology, neuromuscular disorders, gene therapy and/or genome engineering/editing (in particular with CRISPR systems) is highly desirable

Charité offers you

• A fully funded postdoctoral position for two years with salary according to the German public sector (TVöD)
• A highly professional, interdisciplinary and translational work environment, including physicians, basic, translational and clinical researchers, and entrepreneurs
• Intercultural team events, well structured onboarding phase with kind team members

Information regarding the position

• Paygrade E13 according to TVöD VKA-K. You may find further information here
• The position is limited for 14 months, with the possibility of extension
• 30 days of paid vacation per year
• The application period ends on: 25.03.2026
• Position ID: 6456

Application

Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.

Apply using our online tool and become part of the Charité.

Apply now

If you have questions, please contact:

Dr. Helena Escobar ( helena.escobar@charite.de )

Please submit the following documents in connection with your application:

• A cover letter introducing yourself and explaining your motivation for applying
• Your CV, including a list of your publications
• Contact details of one to two referees

Please address your application to Dr. Helena Escobar (helena.escobar@charite.de) and
Prof. Simone Spuler (simone.spuler@charite.de).

Applications will be evaluated on a rolling basis.