Leveraging newly developed brain barrier reporter mouse models, this project will:
• Construct a comprehensive brain barrier atlas at single-cell resolution.
• Investigate 3D anatomy and function of the brain barriers in both health and neuroinflammation
• Utilize cutting-edge imaging techniques including confocal and light sheet microscopy, two-photon imaging, and synchrotron radiation µCT.
• Bridge mouse and human biology by integrating 3D MRI data with histological analysis of human brain tissue.

We are looking for candidates with a keen interest in academic research and a strong foundation in relevant disciplines. Ideal applicants will possess:
• A PhD in the life sciences (e.g., neurobiology, immunology, biomedical sciences).
• A solid background in advanced microscopy and quantitative image analysis.
• Hands-on experience with experimental animal models.
• Knowledge in neuroimmunology and/or neuroscience.
• A collaborative spirit and the ability to thrive in an interdisciplinary research environment.
• Proven scientific writing and publishing experience.
• A strong commitment to building a career in brain barrier biology.
• Excellent communication skills in English (spoken and written)

• A stimulating and appreciative international research environment at the forefront of neuroimmunology and brain barriers biology.
• Access to cutting-edge imaging technologies, unique transgenic mouse models, and collaborative platforms such as the: |Microscopy Imaging Center (MIC) and Data Science Lab (DSL)
•The opportunity to contribute to high-impact translational research.
• A five-year position designed to support professional growth towards independence as a junior group leader.
• A competitive salary in accordance with cantonal regulations.
Start Date: January 1, 2026

Application Deadline: September 5, 2025
To apply, please submit the following documents:
• A cover letter detailing your motivation, relevant qualifications, and future career aspirations.
•Your curriculum vitae, including a list of publications and research achievements.
• Contact details for 2–3 academic references.

Please send your complete application to:
Prof. Britta Engelhardt, Theodor Kocher Institute, University of Bern, Freiestrasse 1, CH-3012 Bern, Switzerland. Email: sekretariat.tki@unibe.ch; Website: www.tki.unibe.ch

This is an exceptional opportunity to join a leading research institute and help shape the future of brain barriers resarch. We look forward to receiving your application.