Our institute is one of the leading centres for clinically oriented immunological research. Our multidisciplinary team of biologists, data scientists, and physicians works closely together on current challenges in clinical immunology research, particularly in inflammatory arthritis. Through advanced in vivo imaging techniques, omics profiling and molecular biological modelling, we seek to unveil the molecular and cellular mechanisms underlying disease resistance, remission, and relapse. Our specialization is the activation and reprogramming of fibroblasts in rheumatic diseases. Find out more about our research: CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis. Nature Immunology , 2024, https://doi.org/10.1038/s41590-024-01774-4 ( https://doi.org/10.1038/s41590-024-01774-4 ) Our lab is part of the newly formed DFG-funded Collaborative Research Center CRC/SFB 1755 CASCAID "Cellular and Systemic Control of Autoimmune Diseases".

We are seeking a motivated scientist (m/f/d) to join our wet lab team.

Tasks

• Creation of high-dimensional multi-omics datasets
• Implementation of state-of-the-art methods into laboratory workflows
• Study of fibroblast activation and reprogramming using sophisticated in vitro and in vivo model systems
• Investigation of cellular cross-talk between fibroblasts and immune cells
• Modeling of clinical findings through advanced experimental systems
• Validation of data mining approaches using experimental model data
• Communication of research strategies and date to the team and the international scientific community

Qualification

• Master's degree (or equivalent), preferably in biochemistry or a related field (molecular biology, cell biology, immunology), either held or due to be completed at the time of application
• Strong interest in immunological research
• Analytical thinking and the ability to work independently
• High level of motivation and commitment
• Excellent written and spoken English

Please provide the following documents in your application:

• Cover letter stating your motivation
• Brief summary of your practical skills and research experience
• Curriculum vitae
• University diplomas including transcripts of records
• Contact details for two academic references, who agree to be contacted during the selection process
• Letters of recommendation

We offer

• Employment in accordance with TV-L (collective agreement for the public sector) based on DFG standards (E13, 65%)
• The opportunity to make a significant research contribution to publication-oriented projects and to write high-quality manuscripts
• Excellent access to state-of-the-art technologies
• Support in presenting your work at international conferences to exchange ideas with the international scientific community
• A strong network of internationally renowned collaborators
• The doctoral candidate (m/f/d) will become a member of the life@FAU graduate school.
• Structured training, mentoring, transferable skills, and a unique infrastructure for team building and exchange opportunities for doctoral candidates

Contact person

Dr. rer. nat. Simon Rauber Junior Arbeitsgruppenleiter Telefon: 09131 85-39592

Applications

Universitätsklinikum Erlangen Department of Medicine 3 Dr. rer. nat. Simon Rauber Ulmenweg 18 91054 Erlangen

Bereitgestellt in Kooperation mit der Bundesagentur für Arbeit.