The Hannover Medical School (MHH), with around 10,000 employees the largest state-owned enterprise in Lower Saxony, is a university institution for research and teaching in human and dental medicine and a university hospital providing supramaximal care. Research, teaching, patient care and administration work hand in hand in an integrated model on the MHH campus.

The DFG-funded Collaborative Research Centre/Transregio CRC/TRR 298 "Safety-Integrated and Infection-Reactive Implants” (SIIRI) awards 10 research fellowships for PhD/MD candidates or Postdocs in either dentistry or medicine, natural sciences, e.g. chemistry, biology and life sciences, engineering sciences, e.g. mechanical engineering, simulation and modelling or data sciences.

Within the SIIRI research network, fundamental mechanisms of implant complications across various medical disciplines are investigated to develop strategies for effective prevention. This is possible due to close transdisciplinary cooperation between dentists, medical doctors, natural, social and engineering scientists from seven universities/institutes (Hannover Medical School (MHH), Leibniz University Hannover (LUH), Hannover University for Music, Drama and Media (HMTMH), Technical University of Brauschweig (TUBs), the Helmholtz Center for Infection Research (HZI), University of Augsburg (UniA) and Johannes Gutenberg University of Mainz (JGU)). The focus is on developing detection and reaction systems that can recognize incipient biological or technical complications early, and prevent or treat them through appropriate measures. The developed systems will merge into a digital implant life cycle management, ultimately leading to a long-term increase in implant safety. Communication research contributes innovatively by examining doctor-patient communication and analyzing how acceptance and trust in new implant technologies can be promoted.