Bioinformatician in Translational Brain Tumor Research and Diagnostics (m/f/d)
from Oct 1st 2025 at the Department of Neuropathology at Heidelberg University Hospital.
The Division of Molecular Neuropathology is seeking an ambitious bioinformatics expert with focus on DNA and RNA sequencing data analysis.
As one of the largest neuro-oncology diagnostic institutions, we are centrally involved in clinical care for thousands of patients annually. We entertain a growing data collection, containing a wealth of data from multi-omics studies, histological imaging, and clinical research. This unparalleled resource provides the foundation for advancing diagnostics through data integration and workflow optimization.
As a key member of our interdisciplinary team - including physicians, biologists, and computer scientists - you will shape the future of data-driven diagnostics. Your primary responsibility will be to iteratively enhance and supervise our next-generation- and third-generation- (Oxford Nanopore) sequencing data pipelines. You will design, implement, and optimize an analysis and interpretation infrastructure tailored for high-throughput data, supporting both clinical reporting and research efforts.
Examples of our prior work in exploring novel methodologies for diagnostics include application of spatial sequencing (Ritter et al., Nat Cancer 2025) or intra-operative longread-sequencing (Patel et al., Nat Med 2025). In this environment with a variety of computational scientists, you can also interact with experts in other areas, including AI-based image analysis, proteomics, spatial and single cell-sequencing.
Together, we aim to continuously translate cutting-edge molecular technology into the care delivery process, creating workflows that surpass traditional single-shot profiling. Your contributions will help integrate data science into every step of oncology care.
- Job-ID: V000014706
- Field of application: Neuropathologie
- Location: Heidelberg
- Job Category: IT
- Working hours: full-time (38,5 Wochenstunden)
- Published: 03.09.2025
- Limitation: Permanent
- Contract: TV-UK
Your tasks
As a key member of our interdisciplinary team, you will:
- Manage, enhance and supervise our NGS/ TGS data analysis workflow
- Develop novel analysis tools at the forefront of sequencing technologies
- Take responsibility for their seamless integration into patient care
- Work with data engineers to implement automated workflows for generating clinical reports and systematic downstream analyses in specialized web applications
- Advance the digital transformation of brain tumor research and diagnostics
Your profile
- A degree in computer science, bioinformatics, or a related field. Applications on various entry levels are welcome
- Experience working with NGS data pipelines, optimally including optimization and integration into complex workflows
- Strong analytical and problem-solving skills, with a structured and results-oriented mindset
- A collaborative spirit and the ability to thrive in an interdisciplinary environment
- Awareness of the clinical relevance of the work
We offer
- Goal-oriented, individual training and development opportunities (e.g. use of AI applications in NGS/ TGS analysis)
- Working with the latest techniques / technical equipment for short- and long-read sequencing
- Flexible working hours within the framework of flexitime
- Possibility of doctorate
- Possibility of habilitation
- Possibility to publish scientifically is offered and supported
- Regular team meetings
- Interdisciplinary cooperation
- A vibrant academic setting in Heidelberg, one of Europe’s top research hubs
- Collectively agreed remuneration (TV-UK E13), attractive company pension scheme (VBL)
- 30 days vacation
- Sustainable travel: job ticket
- Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
- Wide range of health, prevention and sports offers
Interested?
Applications will be accepted until 20.09.2025 via online.
NeuropathologieProf. Dr. Dr. med. Felix Sahm – stv. Ärztlicher Direktor, Neuropathologie
Im Neuenheimer Feld 224
Felix.sahm@med.uni-heidelberg.de
Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.
The UKHD embraces diversity and values diversity.
Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.
Classification is based on qualifications and personal requirements. The salary (gross) is for a full-time position and does not include the annual bonus or other allowances.