Stelle ist zu besetzen ab: 12.01.2026

Beschreibung

Background: This project aims to enhance the mixing performance of NMR-compatible microfluidic chips by incorporating Koch curve geometries into the microchannel design. Koch fractal obstacles have been shown to induce chaotic convection and substantially accelerate passive mixing under laminar flow conditions, achieving efficiencies above 97%. By implementing these elements into a microfluidic channels with active mixing strategy, the project seeks to reduce mixing time, improve the reproducibility of automated, NMR-based protein–ligand binding assays, and enable coupling with hyperpolarization-enhanced detection methods. The outcome will be a faster, more precise microfluidic platform for high-resolution biochemical analysis using operando NMR spectroscopy.

Goal: The objective is to develop an NMR-compatible microfluidic system with significantly improved mixing performance through the incorporation of Koch curve geometries. Approach: The project will develop in three phases:
1. Characterization of the existing system through simulation and experiment to quantify flow dynamics and mixing efficiency.
2. Design and evaluation of Koch curve-based geometries by computational and experimental methods to optimize mixing performance under laminar flow conditions.
3. Manufacturing and implementation of the optimal design in the operando NMR setup. Requirements: You are an ambitious student with a strong interest in microfluidics and automation. Ideally, you have experience in CFD simulations, or computational modeling, and microfabrication, although this is not essential. Supervision:
Dr. Sylwia Barker (sylwia.barker@kit.edu)
Veronika Popova (veronika.popova@kit.edu) Start date is negotiable from 12.01.2026

Art der Anzeige

• Studentische Hilfskraft / Werkstudent:in

Gewünschtes Studium

• Ingenieurwissenschaften
  Chemieingenieurwesen & Verfahrenstechnik
  Maschinenbau
  Sonstige Studienbereiche
  Water Science Engineering
  Mechanical Engineering

Gesuchter Karrierestatus

• Studierende:r

Arbeitsregion

• Karlsruhe und Umgebung

Unternehmensbereich

• Ingenieurwesen und Entwicklung und Konstruktion

Unternehmensbranche

• Wissenschaft & Forschung

Sprache am Arbeitsplatz

• Englisch

Art des Unternehmens

• Wissenschaftliche Einrichtung