The Karl Landsteiner University of Health Sciences (KL) is part of an academic and research community located at the Campus Krems, and includes a network of comprising teaching hospitals in St. Pölten, Krems, Tulln and Eggenburg. KL is committed to raising its profile in specific areas of biomedicine, biomedical engineering, and biopsychosocial sciences by entering into strategic academic and research partnerships with other institutions.

From April 2022 the KL offers a 2-year research position at the Division "Biomechanics" (Head: Univ. Prof. Dr. Dieter Pahr) with the option of getting permanent upon adequate performance :
Research Assistant/ Lab Manager (Post Doc) (40 h) (f/m/d). The Division Biomechanics is part of Prof. Pahr’s Interuniversity Biomechanics Laboratory , which also includes his research group at the TU Wien .

Your tasks:
• Independent experimental research activities in the field of musculoskeletal biomechanics
• Publication activities and writing of applications for external funding
• Teaching and support in administrative tasks
• Supervision of Bachelor, Master and PhD students
• Administration and maintenance of the laboratory infrastructure
• Support of the laboratory head

Your Profile:
• Completion of a suitable doctorate (e.g. mechanical engineering, physics, biomedical engineering, …)
• In-depth knowledge in biomechanical testing (material and/or implant testing incl. programming of measurement data analysis)
• Appropriate track record of publications in scientific journals as well as conference contributions.
• Experience with clinic-related research and imaging techniques (CT or MRI) would be an advantage
• Good German and very good English skills, both written and spoken
• Process-oriented, accurate, structured way of working with a strong ability to prioritize
• Open, resilient and flexible personality with a professional attitude

Your Perspective:
You can expect a challenging job in a highly motivated team. KL is committed to an anti-discriminatory employment policy and values equal opportunities and diversity. KL specifically encourages qualified people with different diversity characteristics (gender, age, ethnicity, denomination, sexual orientation, etc.) to apply. The minimum monthly gross salary for this position is 3,500 € (40 hrs) gross per month. Readiness for overpayment exists with appropriate experience and qualification.

Applications should include a motivation letter, curriculum vitae and credentials and should be mailed by 13th of March 2022 referring to jobnumber "2202” to Ms. Christina Schwaiger of the Karl Landsteiner University of Health Sciences, Dr.-Karl-Dorrek-Straße 30, 3500 Krems, Austria ( bewerbung@kl.ac.at ).

The department of Cell Biology-Inspired Tissue Engineering (cBITE) at the MERLN Institute for Technology-inspired Regenerative Medicine at Maastricht University in the Netherlands invites applications for a post-doctoral position. The post-doctoral researcher will perform cutting-edge research in computational modeling methods applied to regenerative medicine and more specifically, to cell-matrix interactions.

Regenerative medicine (RM) holds the promise to cure many of what are now chronic patients, restoring health rather than protracting decline, bettering the lives of millions and at the same time preventing lifelong, expensive care processes: cure instead of care. The scientific community has made large steps in this direction over the past decade, however our understanding of the fundamentals of cell, tissue and organ regeneration and of how to stimulate and guide this with intelligent biomaterials in the human body is still in its infancy. To date, the RM field has focused on studying cell-biomaterial interactions. Materials properties such as elasticity, topography, hydrophobicity, and porosity have all been shown to influence cell fate, and the introduction of high-throughput combinatorial approaches is expediting research and decoupling the properties to further inform the design of biomaterials. However, in order to improve the design of synthetic biomaterials, it is crucial to understand the physiological cell-ECM interactions and how these influence cell behavior. This research project aims to use in silico models to simulate cell-ECM interactions, improve our fundamental understanding thereof and use the obtained knowledge to design improved synthetic matrices.

Project description:

• Computational modeling of integrin signaling, cell-ECM interaction to inform the design of synthetic matrices;
• Parameter optimization and sensitivity analysis;
• Analysis and integration of various in vitro/in vivo data for model calibration.

What we offer:

• Computational ecosystem at Maastricht University: Institute for Data Science (IDS), Department of Knowledge Engineering (DKE) and Maastricht Centre for Systems Biology (MacsBio);
• Excellent computational and experimental facilities to validate the in silico analyses and predictions in vitro/in vivo;
• Interdisciplinary environment within MERLN and the "Materials-driven regeneration (MDR)-consortium”

Project embedding:

The project will be coordinated by the MERLN Institute for Technology-Inspired Regenerative Medicine ( http://merln.maastrichtuniversity.nl/ ) as part of the "Materials-driven regeneration (MDR)-consortium” (see http://www.mdrresearch.nl/ for more information) which brings together an interdisciplinary team of excellent scientists at three leading institutes (ICMS at Eindhoven University of Technology, RMU at Utrecht University and MERLN at Maastricht University). The central goal of MDR’s research program is to investigate, design and use intelligent biomaterials that drive the functional regeneration of living tissues and organs under complex (patho)physiological conditions.

More information:

For more detailed information you can contact: dr. A. Carlier, email a.carlier@maastrichtuniversity.nl

Do you have a strong technical background in experimental joint biomechanics with an interest in spine biomechanics? Would you like to work as part of a multidisciplinary institute to address a clinically-driven challenge?

We are looking for a proactive individual to join our team of researchers at the Institute of Medical and Biological Engineering at the University of Leeds, leading research on longer lasting joint replacements, tissue sparing interventions and biological scaffolds for tissue regeneration.

This role is created part of an EPSRC project aiming to characterise spinal facet joints biomechanics. In the UK, four out of five adults suffer from back pain at some point in their life, some of which require spinal fusion, an invasive intervention designed to stop the motion of the affected spinal area. After fusion however, facet joint degeneration can increase and create new symptoms and long term pain for one in four patients.

This project will develop novel testing methods and tools combining experimental and computational modelling to gain a better understanding of the degenerated facet joint biomechanics and how it changes following fusion. You will join a wider group developing in vitro and in silico preclinical models of musculoskeletal joints.

You will have a strong background in spine biomechanics or in experimental contact mechanics and have a proactive approach to working in an experimental and computational environment. You will join an institute that includes different expertise and substantial experience in supporting early stage researchers in a key phase of their career. We encourage an environment of collaboration, trust and wellbeing, which values difference of ideas and embraces diversity.

More info (job description and how to apply) available HERE