Hotcherl Jeong
Fähigkeiten und Kenntnisse
Werdegang
Berufserfahrung von Hotcherl Jeong
- 1 Jahr und 6 Monate, Juli 2008 - Dez. 2009
Senior Scientist
Prostemics, Inc.
start-up biotech focusing on secretory proteins from adipose-derived cells
- 1 Jahr, Juli 2007 - Juni 2008
Associate Specialist
University of California, San Francisco
• Developed a novel experimental-computational hybrid strategy for functional analysis of point mutations in human ABC transporters - Functionally characterized 38 disease-associated point mutations - Improved the computational prediction method • Biomarker discovery in irinotecan pharmacogenetics - Genotyped 11 SNPs for candidate transporter genes to search for pharmacogenomic predictors of colorectal cancer drugs and found 2 SNPs that are strongly associated with tumor response to chemotherapy
- 4 Jahre, Juli 2003 - Juni 2007
Postdoctoral Fellow
University of California, Berkeley
• Developed robust cell-based assays examining the functional impacts of SNPs in multidrug-resistance transporters - Quantitatively measured the functional consequences of 10 genetic variants with 4 different drug substrates; This method significantly reduces time and cost in functional analysis of SNPs for early-stage drug safety assessment - Initiated a new methodology in a multidisciplinary pharmacogenomics team, which primarily relied on mouse and human cell lines
- 6 Monate, Jan. 2003 - Juni 2003
Postdoctoral Fellow
University of California, San Francisco
• Developed robust cell-based assays examining the functional impacts of SNPs in multidrug-resistance transporters
Sprachen
Englisch
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