Konstantin Brianv

• Led facility redesign and 2000L bioreactor installation, incl. equipment selection and supplier negotiations. • Eliminated sterilization gap, reducing lead times by 30-56 weeks and saving €60K annually. • Achieved GMP readiness within 1.7 yrs. • Passed 2 GMP inspections on first attempt; hosted 20+ partner visits. • Planned R&D center in Azerbaijan, incl. equipment relocation, customs clearance, and supply chain risks. Repurposed idle tablet block into R&D hub, cutting CAPEX 4× and timelines by 6 months.

• Scaled disinfectant production from ~2.5 t/week to ~25 t/week within three weeks during COVID demand by separating production and filling flows, launching a second filling line, implementing mixing adjustments, and hiring additional staff. • Stabilized raw material supply (isopropanol ~20 t/week) through incoming QC and managing product returns to ensure quality. • Led ISO recertification as Head of QC by preparing documentation, coordinating with the auditor, and successfully extending certifications.

Promoted from Biotechnologist to Process Engineer and then Production Manager • Key technical stakeholder in establishing full-cycle biotech manufacturing from pilot to full-scale GMP production. • Scaled mAb processes (cell culture, cultivation, chromatography, TFF, viral clearance) from pilot to production • Developed overall layout design(22,000 m²) and process flows managed Fill & Finish (aseptic filling, lyophilization) • Provided process input for equipment specifications and commissioning activities

GPA: 4.7/5