Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft. Werde Teil von Roche, wo jede Stimme zählt.

Die Position

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

pRED Cardiovascular, Metabolism, Immunology (CMI), located in Basel, Switzerland, focuses on the discovery and early development of innovative treatments for specific diseases that affect the lives of millions. In the Immunology Department, we are developing cutting-edge therapies to treat chronic inflammatory diseases, including novel treatment options for chronic obstructive pulmonary disease (COPD).

The Opportunity

To complement the Immunology team in pRED CMI, we are seeking a visionary, highly motivated, experienced Scientist with a strong academic background in pulmonary research, a track record in drug target identification and validation and proven ability to effectively lead projectsin a drug discovery setting.

As a Principal Scientist in pRED CMI, you will be a part of an international and multidisciplinary group of scientists and clinicianscommitted to delivering innovative solutions for COPD patients by combining cutting-edge approaches in biology, pharmacology and translational research.

Key Responsibilities:

• Utilising patient data and translational models, you will lead innovative initiatives to gain a better understanding of COPD pathobiology in order to identify novel drug targets and generate therapeutic hypotheses that are experimentally testable, druggable and clinically developable.

• In collaboration with a dedicated team of lab-based associates and post-doctoral scientists, you will direct, oversee and interpret complex preclinical experimental studies for the validation and characterisation of targets or therapeutic agents in COPD.

• You will bring targets into the early drug discovery pipeline and lead multidisciplinary teams up to clinical candidate generation.

• Working in multidisciplinary teams, you will diligently evaluate external opportunities and clearly communicate the findings to senior management

• People management, including coaching and mentoring junior scientists and postdocs

Who You Are

• You hold a PhD degree in Life Sciences (respiratory biology, cellular/ molecular biology, pharmacology, immunology - or a closely related field) and bring 5 to 10 years of experience in the pharmaceutical industry.
• You bring deep expertise in COPD disease biology, including chronic tissue remodelling, inflammation and/ or epithelial biology
• You have significant scientific accomplishments and successful collaborations documented by publications in high-impact journals
• You have a strong strategic thinking capacity, with the ability to balance multiple priorities in a fast-paced, matrixed organisation.
• You have a good understanding of general pharmacological properties of therapeuticmodalities such as small molecules and antibodies.
• You can effectively communicate scientific data and concepts to colleagues, teams and senior management.

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Wer wir sind

Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.

Gemeinsam können wir eine gesündere Zukunft gestalten.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.