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Process Modelling & Simulation Lead – Synthetic Molecules Technical Development

Process Modelling & Simulation Lead – Synthetic Molecules Technical Development

Process Modelling & Simulation Lead – Synthetic Molecules Technical Development

Process Modelling & Simulation Lead – Synthetic Molecules Technical Development

Roche

Pharmazeutische Produkte, Arzneimittel

Basel

    Art der Beschäftigung: Vollzeit
    102.000 CHF – 142.000 CHF (von XING geschätzt)Vor OrtZu den Ersten gehören

Process Modelling & Simulation Lead – Synthetic Molecules Technical Development

Über diesen Job

Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft. Werde Teil von Roche, wo jede Stimme zählt.

Die Position

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted, and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop, and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Opportunity


  • Lead the Modelling & Simulation Centre of Excellence (CoE): Define the strategy, vision, roadmap, standards, and governance for M&S across Synthetic Molecules Technical Development (PTDC), matrix-leading a cross-departmental community of 20+ experts around shared organizational priorities.
  • Drive Strategic Alignment & Leadership: Influence and guide senior leaders across an organization of 700+ employees, proposing innovative ways of working, prioritizing high-impact applications, and serving as a key cross-functional connector without direct formal authority.
  • Shape End-to-End M&S Strategy: Identify where mechanistic, hybrid, and data-driven modelling deliver maximum impact across both Drug Substance and Drug Product lifecycles—from early lab development through scale-up, technology transfer, and commercial manufacturing.
  • Deliver High-Impact Process Solutions: Act as the senior technical authority on complex development challenges, leveraging chemical engineering principles to optimize processes, support experimental design, refine scale-up/scale-down models, and support regulatory submissions.
  • Build Reusable Digital Capabilities: Spearhead the creation of validated model libraries, digital twins, scale-up tools, and self-service applications to establish consistent, scalable modelling standards and reduce duplicated effort across project teams.
  • Drive Organizational Capability & Literacy: Coach and mentor scientists and engineers, elevating M&S literacy across project teams while fostering seamless collaboration between domain experts, modellers, data scientists, and technical partner functions.
  • Connect Roche with External Innovation: Establish external partnerships with universities, research consortia, and technology vendors to evaluate emerging scientific advances and integrate cutting-edge M&S methodologies into the organization.
  • Manage Hardware & Software Strategy: Influence high-value technology investments and vendor partnerships, maintaining governance and decision-making over a six-figure software portfolio.

Who You Are


  • Advanced Academic Foundation: Master’s degree or PhD in Chemical Engineering, Pharmaceutical Sciences, Chemistry, or a closely related discipline.
  • Extensive Process & Modelling Leadership: 12+ years of professional experience in process engineering and M&S within the pharmaceutical or science-based industries, demonstrating deep technical expertise across end-to-end Drug Substance and Drug Product development.
  • Proven Matrix Leadership & Stakeholder Influence: Demonstrated ability to lead complex initiatives across matrixed organizations, challenge the status quo, and align senior decision-makers across PTD and R&D without relying on direct organizational authority to champion, advocate for, and bring visibility to M&S initiatives.
  • Advanced Modelling & Programming Expertise: Hands-on experience with industry-standard modelling platforms (e.g., gPROMS/gWAP, Dynochem) and scientific programming languages (Python, MATLAB), combined with strong knowledge of scale-up/down dynamics and pharmaceutical manufacturing phenomena.
  • Integration of Emerging Technologies: Deep understanding of classical mechanistic modelling, computational fluid dynamics (e.g., COMSOL, M-Star), model-based process control, PAT, and emerging AI/ML paradigms (including hybrid models, digital twins, and agentic AI).
  • Strategic & Conceptual Mindset: Exceptional conceptual thinking skills, with a proven track record of translating complex individual technical problems into reusable model libraries, digital capabilities, and scalable organizational frameworks.
  • Strong Communication & Scientific Collaboration: Fluent in English (written and spoken) with exceptional communication skills to translate sophisticated modelling concepts, assumptions, and limitations into clear, actionable insights for both technical specialists and leaders.

Ready to bring your unique qualities to Roche and make an impact? Apply now and join us in our mission to shape the future of healthcare.

Wer wir sind

Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.

Gemeinsam können wir eine gesündere Zukunft gestalten.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.

Gehalts-Prognose

Unternehmens-Details

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Roche

Pharmazeutische Produkte, Arzneimittel

10.001 oder mehr Mitarbeitende

Basel, Schweiz

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