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The Position

The Opportunity

We are seeking a highly motivated and creative scientist to start a research project within the Nucleic Acid-based Medicine Department at Roche. The focus of the position is to build and develop RNA-based transgenes and synthetic expression systems for Gene Therapy applications. In a highly cross-functional and collaborative team, you will be able to explore and contribute to the engineering of next generation genomic medicines.

The environment is exciting, fast-paced and offers the opportunity to work and publish at the cutting edge of molecular engineering research.

The duration of the RPF project is initially set for two years, with the possibility of extension for a third year. This position is sponsored by the Roche Postdoctoral Fellowship Program. The collaborative research project will be conducted at Roche Basel pRED Center.

Who you are

You hold a PhD in molecular biology, human genetics, biochemistry or related discipline within the fields RNA biology, synthetic biology, or gene therapy. In addition, you have expertise in the following:

• RNA/DNA transgene design

• RNA interference technologies (miRNAs, siRNAs)

• Synthetic biology and pooled screens

• Cell culture and molecular biology methods

• NGS methods and bioinformatics

• Demonstrated skills in designing and performing experiments in hypothesis-driven research, and in establishing innovative techniques

• Proven record of scientific publications

• Excellent oral, written and interpersonal skills are required

Furthermore, you have very good interpersonal and communication skills, are able to build good working relationships and are an outstanding teammate. Your experience and investigative attitude allow you to work independently to design, perform, and interpret experiments, and to embark on new scientific methodologies.

You have been actively engaged in scientific research continuously since your PhD and ready to start an RPF postdoctoral activity no later than 4 years after PhD completion.

The fellowship starts in May 2026 (or upon availability). Please specify your preferred start date in your motivation letter. The duration is 2 years, with the potential for extension.

Please include a CV, motivation letter, and publication list with your application. If you have already received your PhD certificate, please include that as well.

Additional Information

The RPF Program has the ambition to build and maintain the Scientific Leadership of the future and to provide leading Roche scientists with the opportunity to collaborate with talented postdoctoral researchers, and leading academic research groups, from around the world. One of the key aims is to advance basic science and technologies that will be published in top-rated, peer-reviewed scientific journals if necessary preceded by priority patent applications.

More information about the RPF Program: https://careers.roche.com/global/en/the-roche-postdoctoral-fellowship-programme

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.