Leibniz Institute for Food Systems Biology (LSB), Freising

The Leibniz Institute for Food Systems Biology at the Technical University of Munich (Leibniz-LSB@TUM), a legal foundation under civil law based in Freising, is a prominent member of the Leibniz Association. Our institute integrates cutting-edge biomolecular research, bioinformatics, and high-performance analytical technologies to explore the complex interactions between the human organism and food components.

To strengthen our research group Transcriptome & Proteome Profiling / Section I, we are currently looking for a committed Master’s Student for an internship for a duration of 2-3 months to start in March 2026 (earlier or later by arrangement). The topic of the project is "Method Development for Solid-Phase DNA Synthesis”.

About the Project:

Solid-phase DNA synthesis is a fundamental technique in chemical biology and biotechnology, enabling the preparation of defined oligonucleotides for a wide range of research applications.

This project focuses on the experimental development and optimization of solid-phase DNA synthesis methods, including reaction workflows, process parameters, and analytical evaluation of synthesized oligonucleotides. The work is part of an ongoing PhD project and involves hands-on laboratory experimentation, systematic troubleshooting, and data-driven optimization.

Key Responsibilities:

• Perform solid-phase synthesis of short DNA oligonucleotides
• Assist in optimization of synthesis conditions
• Analyze synthesized oligonucleotides using PAGE, HPLC and LC-MS
• Support troubleshooting procedures and results according to good scientific practice
• Critically evaluate and discuss experimental outcomes

Ideal Applicants Must Have:

• A background in chemistry, chemical biology, biochemistry, or a related field.
• Basic knowledge of organic or biomolecular chemistry.
• Interest in nucleic acid and photochemical chemistry is advantageous but not required.
• Ability to work independently with attention to detail.
• Willingness to work on iterative optimization and troubleshooting tasks.
• Good written and verbal English communication skills.

We are seeking a highly motivated individual with excellent interpersonal communication, time-management skills, commitment to laboratory safety and handling laboratory equipment with care. We are looking for a team player, who can work independently as well. This offer is aimed exclusively at students.

What we offer:

• a respectful and collegial working atmosphere
• an interesting and responsible role in the context of cutting-edge non-university research
• Close supervision and structured training in solid-phase synthesis and analytical techniques
• Hands-on experience with nucleic acid chemistry and method development
• A supportive and collaborative working atmosphere
• flexible working hours to support a healthy work-life balance
• a motivated team looking forward to welcoming you

Equal Opportunities and Diversity:

Leibniz-LSB@TUM is committed to equal opportunities, diversity, and a respectful working environment. We welcome applications regardless of gender, nationality, ethnic or social origin, religion or belief, disability, age, or sexual orientation and identity.

Applicants with severe disabilities or those with equivalent status will be given preferential consideration in cases of essentially equal qualification (§ 2 SGB IX).

Contact and Application:

For any inquiries regarding the advertised position, please contact: Santra Santhosh, s.santhosh.leibniz-lsb(at)tum.de.

More information on the working group can be found here: https://www.leibniz-lsb.de/en/research/research-sections/section-i.

Please send your application, including a tabular CV, motivation letter and current transcript of records, as a PDF file and stating the reference number 2026-03-S1-SS via email to: Santra Santhosh (PhD Student) s.santhosh.leibniz-lsb(at)tum.de and Anja Albrecht (Administration) recruiting.leibniz-lsb(at)tum.de.

We look forward to receiving your application!

Data Protection Notice:

As part of your application for a position at Leibniz-LSB@TUM, you will transmit personal data. Please refer to our data protection information in accordance with Article 13 of the General Data Protection Regulation (GDPR) regarding the collection and processing of personal data in the context of your application. By submitting your application, you confirm that you have taken note of the Leibniz-LSB@TUM data protection information.