Master Thesis on Electrochemically Controlled Selective Diazotization and Azocoupling Chemistry (Flexible Starting Dates)

27.07.2026, Studentische Hilfskräfte, Praktikantenstellen, Studienarbeiten

Hier finden Sie Stellen für Studentische Hilfskräfte, Praktikantenstellen an der TU München sowie Studienarbeiten

Diazotization and azo coupling are among the most important transformations in organic synthesis,
underpinning the production of dyes, pharmaceuticals, molecular probes, and functional materials.
The formation of aryl diazonium intermediates, however, remains inherently challenging because
of their thermally instability and, in some cases, potentially explosive, requiring their in-situ
generation and immediate consumption. Consequently, conventional diazotization typically relies
on multistep protocols involving strong acids low temperatures (0-5°C), and sequential pH
adjustment to facilitate diazotization followed by azo coupling. These stringent reaction conditions
increase process complexity, safety risks, and waste generation while limiting precise control over
reaction selectivity and intermediate stability.
In this project, we design an electrochemical one-pot synthetic platform that integrates
diazotization and azo-coupling within a single reaction system through spatially controlled
electrochemical reaction environments. Using the synthesis of Sunset Yellow FCF as a model
system, this work aims to elucidate the kinetics and mechanism of electrochemically regulated
diazotization as a general platform for controlling acid–base-dependent organic transformations
and selective azo-coupling reactions.
What do you bring?
• Interest in electrochemistry and/or organic chemistry (preferred, not mandatory)
• You are enrolled in a degree program at TUM or another German university
• Motivation to learn new things
• Ability to think critically about data
• Experience working in a chemistry lab
What do we offer?
• Opportunity to work on electrochemical experiment and system design
• Close supervision
• Fundamental understanding of electrochemical concepts
Are you interested? Please, contact pooja.sindhu@tum.de with your CV for further information.

Kontakt: pooja.sindhu@tum.de