Semester/Master’s thesis - Enzymatic cell disruption of filamentous fungi

11.08.2025, Studentische Hilfskräfte, Praktikantenstellen, Studienarbeiten

The focus of my project is on particularly lectins (protein) and β-glucans (polysaccharides) to extract and separate them from fungi using efficient downstream unit operation.

The part of the project here is to study the cell disruption of fungi with different enzymes which willl break down the tough cell wall of the fungi. It is also important to study the enzyme kinetics for the disruption of cell wall. And also important to study the combination of enzymes and also combine different cell disruption method for the best possible cell disruption.

Objective-
To study different enzymes for the cell wall disruption
To study enzyme kinetics
To study the combination of enzymes for cell disruption
To combine best combination with other method
Analytical Technique: SDS page, Protein analytical technique, Hemagglutination assay.

Profile-
Structured and independent work
Motivation to work as a team/ willing to learn
Master student in chemical engineering, biotechnology (IBT, MBT),Pharmaceutical biotechnology biochemistry, chemistry, microbiology, or similar
Start date: as soon as possible or in Oct
Language: English
Lab experience : Ideal

Kontakt: Bhagyeshri Ulhas Mantri, b.mantri@tum.de , Chair of Bioseperation Engineering