At smartbax, we aim to introduce the next generation of antibiotics. We develop novel antibacterial compounds with extraordinary potency against multi-drug resistant bacteria and hijack bacterial pathways that no other drug has touched before. As a start-up in Munich’s vibrant biotech scene, we offer an environment where your work makes a real difference. Help us pioneer new therapies that will save lives.

We are looking for a Senior Scientist (PhD) with expertise in structural biology and data science, full-time, starting immediately, to join our growing team.

• Structure-guided optimisation of small molecule antibiotic candidates through both in silico and experimental analyses
• Docking and molecular modelling studies to inform medicinal chemistry decision making
• Co-crystallization experiments with test compounds and target enzymes
• Coordination with CROs
• Implementation of AI and machine learning approaches for data analysis, compound design and property prediction
• Data evaluation, visualisation and presentation towards the team, shareholders and investors
• Creative and critical thinking in solving scientific problems

• PhD in structural biology, computational chemistry or related subjects
• Experience in working with proteins and analysing small molecule-protein interactions
• Strong computational and programming skills, including docking, molecular dynamics, machine learning and AI
• Additional expertise in handling S2 bacteria is considered a plus
• Self-organised, enjoys working in small teams
• Creative, fast-thinking and decisive mind who likes tackling challenges
• Proficient in written and spoken English; German skills are a plus

• Purpose: Contribute to the fight against antimicrobial resistance, one of the greatest healthcare challenges of our time
• Freedom and agility: Flat hierarchy, fast decision making, and no unnecessary bureaucracy, allowing you to focus on things that really matter
• Shaping the company’s future: Responsible position with direct impact and room for creativity in a highly motivated and experienced team
• A workplace tailored to your needs: 40 hours per week with flexible start and end times, brand-new lab and office spaces, and the freedom to work from home when needed
• Attractive benefits: Monthly vouchers for personal use (e.g. groceries, wellness, etc)
• Step into the future of biotech: Join a cutting-edge biotech start-up in Munich, driving innovative drug development with strong venture capital support

Start: Immediately | Location: Munich/Neuherberg (Life Science Factory at the Helmholtz Pioneer Campus)

Interested to join the smartbax team? We look forward to receiving your application with a short cover letter, CV and availability.