Senior Scientist Biologics - Early Drug Candidates (100%)
Senior Scientist Biologics - Early Drug Candidates (100%)
Senior Scientist Biologics - Early Drug Candidates (100%)
Senior Scientist Biologics - Early Drug Candidates (100%)
GlycoEra AG
Bio- und Nanotechnologie
Wädenswil
- Verifizierte Job-Anzeige
- Art der Anstellung: Vollzeit
- 92.000 CHF – 141.000 CHF (von XING geschätzt)
- Vor Ort
- Zu den Ersten gehören
Senior Scientist Biologics - Early Drug Candidates (100%)
Über diesen Job
Intro
Join a motivated cross‑functional team to drive early‑stage biologic drug candidates from design through process development and characterization, powered by hands‑on laboratory experimentation to build and elevate our pipeline portfolio
Tasks
- Design, express, purify and optimize novel (glyco)proteins for early drug candidates, apply novel and state-of-the-art approaches and lab experiments
- Scale expression from shake flasks to fed‑batch bioreactors; harvest, purify and prepare material
- Analyze critical quality attributes using methods such as SDS‑PAGE, ELISA, HPLC, LC‑MS, SEC, CE and SPR
- Maintain meticulous experimental records; prepare technical reports and presentations
- Ensure compliance with SOPs, GMP, regulatory and quality standards
Requirements
- Ph.D. in Biochemistry, Molecular Biology, Biotechnology or related field
- Minimum of 4 years industrial Biologics experience in protein biochemistry and bioprocess development
- Proven experience in engineering, expressing and purifying glycoproteins, mAbs or scaffolds
- Hands‑on experience with upstream/downstream scale‑up and bioreactor operations
- Sound experience with fast protein liquid chromatography using standard equipment like Äkta and different chromatography techniques
- Proficiency in analytical protein characterization / CQAs
- Solid background in genetic engineering, clone selection and cell line development
- Experience using in silico/AI‑driven protein engineering and developability tools is a plus
- Familiarity with GMP regulations and quality systems
- Proactive problem‑solver who can multitask in fast‑paced environments
- Excellent written and spoken English communication
Closing
If this role matches your profile, please upload your CV and motivation letter.