CRS Clinical Research Services

CRS Clinical Research Services

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201-500 Mitarbeitende

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CRS Clinical Research Serviceshat einen Beitrag geschrieben.26. Juni 2024

TEAM LEAD HUMAN RESOURCES (w/m/d) in Vollzeit - Deutschlandweit Wir sind eines der größten Auftragsforschungsinstitute (Phasen I und II) in Europa mit mittlerweile mehr als 40 Jahren Erfahrung in der internationalen klinischen Arzneimittelforschung. In unseren Studienzentren arbeitet ein Team von insgesamt 250 Mitarbeiterinnen und Mitarbeitern deutschlandweit vernetzt zusammen. Für unsere Gruppe suchen wir deutschlandweit zum nächstmöglichen Zeitpunkt eine/n TEAM LEAD HUMAN RESOURCES (w/m/d) in ...

Team Lead Human Resources (m/w/d) - Job Mobiles Arbeiten - Jobs@CRS

Ansprechpartner für alle Fach- und Führungskräfte, sowie für die Geschäftsleitung der Unternehmensgruppe Führung des Teams der Personalabteilung Führen des...jobs.crs-group.de

CRS Clinical Research Serviceshat einen Beitrag geschrieben.22. März 2024

CRS eröffnet ein neues Kapitel mit der Ernennung von Elisabeth Lackner, einer führenden Branchenexpertin, zur Geschäftsführerin: Wir freuen uns, Dr. Elisabeth Lackner als neue Geschäftsführerin von CRS Clinical Research Services seit dem 15. März 2024 bekannt zu geben. Herzlich willkommen, @Elisabeth Lackner! Frau Dr. Lackner ist mit der Leitung der zukünftigen strategischen Ausrichtung des Unternehmens betraut und wird die Internationalisierung des Unternehmens vorantreiben und das Dienstleistu...

CRS Clinical Research Serviceshat einen Beitrag geschrieben.8. Februar 2024

🎉 We are pleased to announce that CRS Clinical Research Services is now a member of InnoNet HealthEconomy e.V. As part of this dynamic network, we connect with the most innovative players in the healthcare industry in Rhineland-Palatinate and neighboring regions. 🤝 Our aim is to promote interaction between politics, healthcare and business and to work together on forward-looking solutions. We look forward to being part of this collaboration and to the exciting opportunities that membership o...

CRS Clinical Research Serviceshat einen Beitrag geschrieben.1. Februar 2024

Have you already read this interesting publication on Journal of Diabetes & Metabolic Disorders? 📑 📢 Check out the study “Non alcoholic fatty liver disease in obese subjects as related to increasing insulin resistance and deteriorating glucose control: Three years of follow up from a longitudinal survey” to delve into the key findings and implications. We congratulate the team for their hard work and dedication! Read the publication here: https://link.springer.com/article/10.1007/s40200-023-0 ...

Non-alcoholic fatty liver disease in obese subjects as related to increasing insulin resistance and deteriorating glucose control: Three years of follow-up from a longitudinal survey - Journal of Diabetes & Metabolic Disorders

Purpose This observational trial was performed to evaluate liver parameters in overweight or obese subjects in the context of insulin resistance and glucose control over time. Subjects/Methods Insulin resistance, glucose control and several parameters for liver integrity were monitored in 177 overweight (BMI > 28 kg/m2) subjects over a mean of 30 months. Volunteers were categorized according to insulin resistance (HOMAIR score) and glucose control in subjects with normal glucose control (NGT), impaired glucose control (IGT), or diabetes mellitus type 2 (T2DM). Liver fat and fibrosis were evaluated by sonographic elastography (FibroScan®) and clinical scores, such as the AST/ALT ratio, fatty liver index (FLI), and NAFLD fibrosis score (NFS). Results Liver fat fraction as estimated by the controlled attenuation parameter (CAP), and the FLI were significantly higher in subjects with T2DM compared to IGT and NGT. While fasting insulin levels and the HOMAIR score continuously increased over time, no change in CAP or FLI occurred during follow up. CAP was correlated with FLI (r = 0.50; p < 0.0001) and the HOMAIR score (r = 0.32; p < 0.0001). An inverse correlation was observed between serum adiponectin levels and FLI (r = -0.37; p < 0.0001), the HOMAIR score (r = -0.19; p < 0.001, and CAP (r = -0.15; p < 0.01). Conclusions In subjects with a BMI ≥ 28 kg/m2, liver fat fraction is significantly elevated in those with T2DM compared to IGT or NGT. Liver fat fraction is associated with deteriorating insulin sensitivity and loss of glucose control. Despite a continuous increase in insulin resistance, no change in liver fat content or stiffness occurred over 30 months.link.springer.com

CRS Clinical Research Serviceshat einen Beitrag geschrieben.10. Januar 2024

Have you already read this interesting publication on British Journal of Clinical Pharmacology? 📑 📢 Check out the study “Effect of changes in metabolic enzymes and transporters on drug metabolism in the context of liver disease: impact on pharmacokinetics and drug-drug interactions” to delve into the key findings and implications. We congratulate the team for their hard work and dedication! Read the publication here: https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.15990 #medical #...

CRS Clinical Research Serviceshat einen Beitrag geschrieben.3. Januar 2024

Have you already read this interesting publication on PubMed? 📑 📢 Check out the study “The Role of Ultra-Rapid-Acting Insulin Analogs in Diabetes: An Expert Consensus” to delve into the key findings and implications. We congratulate the team for their hard work and dedication! Read the publication here: https://pubmed.ncbi.nlm.nih.gov/37937585/ #medical #publication #release #research #publicationrelease #researchhighlights #clinicaltrials #scienceanddiscovery

CRS Clinical Research Serviceshat einen Beitrag geschrieben.5. Dezember 2023

Have you already read this interesting publication on PubMed? 📑 📢 Check out the study “Pharmacokinetics, Safety, and Tolerability of the Novel Tetrameric, High-Relaxivity, Macrocyclic Gadolinium-Based Contrast Agent Gadoquatrane in Healthy Adults” to delve into the key findings and implications. We congratulate the team for their hard work and dedication! Read the publication here: https://pubmed.ncbi.nlm.nih.gov/37921759/ #medical #publication #release #research #publicationrelease #researc...

Pharmacokinetics, Safety, and Tolerability of the Novel Tetrameric, High-Relaxivity, Macrocyclic Gadolinium-Based Contrast Agent Gadoquatrane in Healthy Adults - PubMed

Gadoquatrane with its high-relaxivity, pharmacokinetic similarity to established Gd-based contrast agents and high tolerability is a promising "next-generation" contrast agent for magnetic resonance imaging.pubmed.ncbi.nlm.nih.gov

CRS Clinical Research Serviceshat einen Beitrag geschrieben.23. November 2023

Have you already read this interesting publication on PubMed? 📑 📢 Check out the study “Effect of nivasorexant (ACT-539313), a selective orexin-1-receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in healthy subjects” to delve into the key findings and implications. We congratulate the team for their hard work and dedication! Read the publication here: https://pubmed.ncbi.nlm.nih.gov/37800597/ #medical #publication #release #resea...

Effect of nivasorexant (ACT-539313), a selective orexin-1-receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in healthy subjects - PubMed

Nivasorexant, a selective orexin-1-receptor antagonist, has recently been assessed in the treatment of humans with binge-eating disorder. Herein, the inhibitory potential of nivasorexant on cytochromes P450 (CYPs) 2C9, 2C19, and 3A4 was evaluated. Human liver microsomes/recombinant CYP enzymes were …pubmed.ncbi.nlm.nih.gov

CRS Clinical Research Serviceshat einen Beitrag geschrieben.21. November 2023

✨We are pleased to announce that Professor Dr. Forst, along with other experts, has contributed to a special article on Diabetology and Metabolism. The article offers valuable insights into the latest developments and research in this important field. You can find the article on Thieme's website via the following link: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-2076-0175#info The topic is especially relevant to us, as we conduct clinical studies related to diabetology,...

Thieme E-Journals - Diabetologie und Stoffwechsel / Abstract

Thieme E-Books & E-Journalswww.thieme-connect.de

CRS Clinical Research Serviceshat einen Beitrag geschrieben.17. November 2023

Exciting news! From November 29th to 30th Ulrika Martensson will attend the Nordic Life Science Days in Copenhagen🌎 The fact that she is apparently a common participant can already be seen from the photo on the Nordic Life Science Fair website 😉. This event is a fantastic opportunity to explore the latest advances in the life sciences and make valuable connections. We are proud to be part of this dynamic industry and wish Ulrika a successful and inspiring experience! Learn more about the pr...

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CRS. Experts. Early Phase. Wir sind eines der führenden Auftragsforschungsinstitute (Phasen I und II) in Europa mit mittlerweile 40 Jahren Erfahrung in der internationalen klinischen Arzneimittelforschung. An unseren Klinikstandorten führen wir im Auftrag zahlreicher internationaler Hersteller von Medikamenten und...

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