Dr. Andreas Rybka
Fähigkeiten und Kenntnisse
Werdegang
Berufserfahrung von Andreas Rybka
- Bis heute 5 Jahre und 7 Monate, seit Nov. 2019
Head of Chemistry
Aelin Therapeutics
Leading a team (14 FTE) responsible for synthesis, bioanalytics, biophysical characterization and formulation development of peptides.
- 1 Jahr und 4 Monate, Aug. 2018 - Nov. 2019
Manager DP Biologics
Eurofins Amatsigroup
- 2 Jahre und 4 Monate, Apr. 2016 - Juli 2018Teva ratiopharm
Senior Manager Global Technology Center (Peptide Formulation / 3D Printing)
Creation, evaluation and implementation of promising new technologies for the pharmaceutical industry to fulfill patients needs. Concepts for oralisation of peptides, delivery of APIs through the blood brain barrier, oralisation of APIs by smart pills (magnetic, mechanical, electric systems), 3D printing of API containing filaments (FDM). EHS-Management within division. Education-Management within division.
- 5 Jahre und 6 Monate, Okt. 2010 - März 2016
Head of Peptide Chemistry
Nexigen GmbH
Leading a lab responsible for peptide synthesis (conventional solid phase, microwave assisted peptide synthesis, peptide arrays). Modification, purification (LC-MS), analysis (ESI-MS, HPLC, UPLC), stability assays and formulation development of peptides. EHS-Management within division. Supervising CMC within further advanced projects. Company focus: peptides targeting intracellular protein-protein interactions (cancer stem cells). Project management in preclinical development (CMC) and delivery projects.
- 7 Jahre und 11 Monate, Okt. 2002 - Aug. 2010
Director of Peptide Chemistry
AplaGen GmbH
Leading a lab responsible for peptide synthesis (conventional solid phase, microwave assisted peptide synthesis, peptide arrays). Modification, purification (LC-MS), analysis (ESI-MS, HPLC, UPLC), stability assays and formulation development of peptides. EHS-Management within company. Company focus: EPO mimetic peptides, technologies for half life extension of peptides.
- 7 Monate, März 2002 - Sep. 2002
Postdoctoral fellowship
Universitätsklinikum Essen
Optimization of a purification method for bioactive proteins (Hydrophobic Interaction Chromatography).
- 1 Jahr und 8 Monate, Juni 2000 - Jan. 2002
Lab Manager Proteomics
Innotides AG
Leading a lab responsible for peptide synthesis, modification, purification (LC-MS), analysis (ESI-MS, HPLC). Company focus: peptides targeting IL2, IFNa, TRAIL.
Ausbildung von Andreas Rybka
- 3 Jahre und 2 Monate, Juni 1996 - Juli 1999
Peptide Chemistry
Ruhr-University Bochum
Involved in synthesis, purification and analysis of peptides and peptidomimetics. Additionally working on conformational analysis of peptides and peptidomimetics with NMR (1D-2D) and molecular modelling. PhD-thesis: Template fixed cyclic peptide structures – Synthesis and conformational analysis.
- 8 Monate, Okt. 1995 - Mai 1996
Peptide Chemistry
Ruhr-University Bochum
Involved in synthesis, purification and analysis of peptides and peptidomimetics. Additionally working on conformational analysis of peptides and peptidomimetics with NMR (1D-2D) and molecular modelling. Diploma thesis: Aromatic linkers as scaffolds for parallel peptides - Synthesis and NMR analysis
- 5 Jahre und 8 Monate, Okt. 1990 - Mai 1996
Organic Chemistry
Ruhr-University Bochum
Basic study period (Organic Chemistry).
Sprachen
Deutsch
Muttersprache
Englisch
Fließend
Französisch
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