Dr. Andreas Rybka
Fähigkeiten und Kenntnisse
Werdegang
Berufserfahrung von Andreas Rybka
- Current 6 years and 7 months, since Nov 2019
Head of Chemistry
Aelin Therapeutics
Leading a team (14 FTE) responsible for synthesis, bioanalytics, biophysical characterization and formulation development of peptides.
- 1 year and 4 months, Aug 2018 - Nov 2019
Manager DP Biologics
Eurofins Amatsigroup
- 2 years and 4 months, Apr 2016 - Jul 2018
Senior Manager Global Technology Center (Peptide Formulation / 3D Printing)
Teva ratiopharm
Creation, evaluation and implementation of promising new technologies for the pharmaceutical industry to fulfill patients needs. Concepts for oralisation of peptides, delivery of APIs through the blood brain barrier, oralisation of APIs by smart pills (magnetic, mechanical, electric systems), 3D printing of API containing filaments (FDM). EHS-Management within division. Education-Management within division.
- 5 years and 6 months, Oct 2010 - Mar 2016
Head of Peptide Chemistry
Nexigen GmbH
Leading a lab responsible for peptide synthesis (conventional solid phase, microwave assisted peptide synthesis, peptide arrays). Modification, purification (LC-MS), analysis (ESI-MS, HPLC, UPLC), stability assays and formulation development of peptides. EHS-Management within division. Supervising CMC within further advanced projects. Company focus: peptides targeting intracellular protein-protein interactions (cancer stem cells). Project management in preclinical development (CMC) and delivery projects.
- 7 years and 11 months, Oct 2002 - Aug 2010
Director of Peptide Chemistry
AplaGen GmbH
Leading a lab responsible for peptide synthesis (conventional solid phase, microwave assisted peptide synthesis, peptide arrays). Modification, purification (LC-MS), analysis (ESI-MS, HPLC, UPLC), stability assays and formulation development of peptides. EHS-Management within company. Company focus: EPO mimetic peptides, technologies for half life extension of peptides.
- 7 months, Mar 2002 - Sep 2002
Postdoctoral fellowship
Universitätsklinikum Essen
Optimization of a purification method for bioactive proteins (Hydrophobic Interaction Chromatography).
- 1 year and 8 months, Jun 2000 - Jan 2002
Lab Manager Proteomics
Innotides AG
Leading a lab responsible for peptide synthesis, modification, purification (LC-MS), analysis (ESI-MS, HPLC). Company focus: peptides targeting IL2, IFNa, TRAIL.
Ausbildung von Andreas Rybka
- 3 years and 2 months, Jun 1996 - Jul 1999
Peptide Chemistry
Ruhr-University Bochum
Involved in synthesis, purification and analysis of peptides and peptidomimetics. Additionally working on conformational analysis of peptides and peptidomimetics with NMR (1D-2D) and molecular modelling. PhD-thesis: Template fixed cyclic peptide structures – Synthesis and conformational analysis.
- 8 months, Oct 1995 - May 1996
Peptide Chemistry
Ruhr-University Bochum
Involved in synthesis, purification and analysis of peptides and peptidomimetics. Additionally working on conformational analysis of peptides and peptidomimetics with NMR (1D-2D) and molecular modelling. Diploma thesis: Aromatic linkers as scaffolds for parallel peptides - Synthesis and NMR analysis
- 5 years and 8 months, Oct 1990 - May 1996
Organic Chemistry
Ruhr-University Bochum
Basic study period (Organic Chemistry).
Sprachen
German
C2 (Verhandlungssicher / Muttersprachlich)
English
C1 (Fließend)
French
A1-A2 (Grundkenntnisse)
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