Dr. Annika Brings

- Assessment of clinical and molecular knowledge around the relationship between patient/tumor genotypes and responsiveness to drug treatments - Compilation of evidence-based summaries of scientific literature

• Monitoring of clinical studies according to good clinical practices • Primary study contact for clinical trial sites

- Translational Pharmacokinetic/pharmacodynamic modelling in Oncology

- Development of mathematical models describing the drug pharmacokinetics (PK) and pharmacodynamics (PD) based on preclinical data - Model-based design of preclinical studies and human dose estimation - Close interaction with interdisciplinary project teams - Presentation of results in meetings and on conferences

PhD student in the Experimental Therapeutics group of Prof. Dr. Bill Wilson at the Auckland Cancer Society Research Centre; design, execution, documentation & interpretation of in vitro, in vivo and in silico studies; presentation of results in meetings and on conferences; scientific writing

Hypoxia-activated prodrugs, Extravascular drug transport, Mathematical modeling of drug pharmacokinetics/pharmacodynamics in tumour tissue, Tumour microenvironment

Pharmacology, Medicinal Chemistry, Gene expression & replication, Chemical Biology of Carbohydrates

Enzymology, Protein & DNA structure

Biology: Biochemistry, Cell Biology, Genetics, Biophysics, Immunology, Physiology, Medicine, Toxikology, Microbiology Chemistry: Organic, Physical, Anorganic and Analytical Chemistry