Dr. Chantal Roth

- Mixture deconvolution and number of contributor algorithms using machine learning for forensics - Design and development of forensics DNA profile search algorithm (supporting both STR and NGS) and design of an extensible framework - Design and development of mtDNA variant caller, custom mtDNA specific Smith-Waterman algorithm and mito IGV plugin to view and edit mtDNA variants (forensics)

• Management of software engineering group of 8-10 people • Design and development of IRobot, a robot schedule optimization application • Design and development of Symphony, a general workflow application framework that is able to support any kind of workflow and process based on ontologies • Continued and lead development of bioinformatics platform BioSphere for Syngenta, including viewers and editors for metabolic pathways, expression data and search tools

• Project lead, design and implementation of BioSphere, a globally deployed bioinformatics platform to visualize and integrate various sequence related data • Designed and developed Saphire, a general reusable full stack architecture including persistence framework, graphics framework and application framework (like Spring) • Development of a generic data/XML loader for various db systems • Designed and implemented a template based code generator (and O/R mapping tool)

Computational Biology

Molekularbiologie, Genetik