Chennakesava Cuddapah

Invitro testing for cosmetic and biotech industries using human primary cell cultures and 3D models (with cell types such as primary keratinocytes, fibroblasts, melanocytes and adipocytes derived from human skin).

1. Immunobiology of citrunillated antigens and antibodies in human autoimmune disease Rheumatoid Arthritis (in human neutrophils, serum and plasma) Techniques: Antibody purification, ELISA development, protein purification and processing for Mass spectrometric analysis, isolation of neutrophils from synovial fluid cells

1. Immune function of microchimeric cells in human autoimmune disease Systemic Sclerosis/Scleroderma and Transplantation. (in human cell types such as primary skin micro-vascular endothelial cells, T & B lymphocytes, granulocytes, human bone marrow cells and in human tissues such as skin and lung) 2. HLA genetics of human autoimmune disease Systemic Sclerosis/Scleroderma. (High resolution HLA genotyping)

Antigen (viral and endogenous) processing and presentation by human primary vascular endothelial cells and their recognition by cytotoxic T cell lymphocytes.

Development of male contraception: Identification of estrogen regulated genes in the epidydimis of Macaca radiata (Bonnet monkey) for the

During my doctoral thesis, I worked on the role of receptor tyrosine kinase EphB4 and its ligand EphrinB2 during normal human placental development (angiogenesis and vasculogeneis) and in placental disorder pre-eclampsia. (in human primary trophoblast epithelial cells, human primary umbilical cor