Dr. Christina Daschkin

Head of R&D - infection diagnostics - routine and development - research-lab management - assay development - microbiology and molecular biology

• Cloning and recombinant production of target enzymes • Protein purification and analysis via chromatography • Quality inspection of proteins • In vitro characterization of small-molecule inhibitors • Binding studies (MST) • Bacterial growth assays (MIC-determination of clinical isolates, compound testing) • Presentations for cooperation partners and conferences • Supervision of students and technical staff • Advanced training: Design of Experiments, Time Management, Emotional Competence

• Cloning and recombinant production of target enzymes • Protein purification and analysis • Quality inspection of proteins • Development and Validation of screening-assays • Compound / Library screening • Preparation of bacterial knock-out strains • Serum production and processing • Analysis of sera and antibodies • FACS analysis of bacteria • Bacterial growth assays • Presentations for cooperation partners and conferences

Masterthesis: „Kristallographische Charakterisierung von Hem H aus P. falciparum und M. tuberculosis“ Cloning, Protein Production and Chromatography, Anaerob Procedure, Enzymatic Activity of Ferrochelatase, Crystallization Screen Lehrstuhl für Biochemie - Prof. Groll, Fakultät für Chemie, TU München

Expression und Reinigung von HemG aus Mycobacterium tuberculosis und Plasmodium falciparum

Histologische Bestimmung von Leukozyten im bovinen Endometrium während der Präimplantationsphase

Quantifizierung von Acetaldehyd durch Headspace-vermittelte Probengewinnung und GC-MS

Anwendung der PLA-Methode zur Identifizierung coexprimierter Proteine in Paraffingewebe aus Mammakarzinomen

Fluoreszenzuntersuchungen an der kleinen GTPase Toc34 aus dem Translokationskomplex der äußeren Chloroplastenhülle

Enzyme der bakteriellen Fettsäurebiosynthese: FabG, FabK, FabI

„Combating Bacterial Infections with Novel Small-Molecule Therapeuticals – Target Identifications, Assay Development and Compound Screening“