Frank Sievert

Authorisation to act Identification and implementation of innovative technologies to develop novel products with additional patients' benefit Conceptual design and development of Global Technology Center Implementation of additive manufacturing (2D/3D printing) as a tool for personalized dosing and adherence enhancement, digitalised manufacturing. This includes formulation and printer development. Public funding for additive manufacturing projects

42 reports (direct and indirect Budget Responsibility: 10 mio € Identification of future relevant generic products by evaluating innovator's development pipeline Ensure generic launch with expiry of basic patent. Design around prolonging originator's patents. Securing freedom to operate for own development by suitable measurements including own intellectual property Evaluation and establishment of new technologies International project teams Qualification as “Qualified Person” acc. AMG

Implementation of Pharmaceutical Research as a new unit for innovation and added valued products . Authorisation to act 5 heads of department and 1 project manager as direct reports, 46 indirect reports, internationally organized (India, Swizerland, Germany) Conceptional design and implementation of Pharmaceutical Research as a new unit for innovation and added valued products Identification of future relevant generic products by evaluating innovator's development pipeline

Authorisation to act 3 Scientists as direct reports, 15 indirect reports Budget: 1 mio € Key responsibilities: Formulation development for New Chemical Entities (NCE) Formulation development for generics Process optimization Trouble Shooting Clinical trial supply Head of production clinical trials according AMG § 14

Key responsibilities: Implementation of formulation development in the company Manufacturing of clinical trial samples Support of production with trouble shooting and process development

Reporting to Head of production Authorised to give instructions to production staff Key responsibilities: Production trouble shooting Creation of manufacturing documentation (GMP) In process control Process optimization

Formulation development Key responsibilities: - Formulation development of all dosage forms (solids, semi solids, liquids) - Manufacturing of clinical trial samples - Qualification according AMG §14 (“Herstellungsleiter”)

Pharmacist inseveral public pharmacies for holliday replacement of resposible pharmacist