Dr. Haresh Ajani

Computational Chemist expert with 7+ years of experience in the Pharmaceutical Industry research expertise, an EU Marie Curie Individual Fellow in Computational Drug Design and Computational Chemistry. Interdisciplinary collaborator with working experience with medicinal chemists, biologists, and pharmacologists on Drug Discovery Projects.

--> Designed and discovered novel inhibitors of RBBP4 and Kinases using SBDD, LBDD, and Cheminformatics methods. -->Developed and designed Structure-Based PROTAC Design computational method for PROTAC discovery using Protein-protein docking (Rosetta, Haddock, ICM). --> Designed and screened a Proteolysis Targeting Chimeras (PROTAC) library for protein degradation targets. --> Application of Structure-Based PROTAC Design computational method for hit identification, and lead optimization of PROTAC.

--> Coordinated the design of individual projects, providing ongoing mentoring support and collaborating with medicinal chemists, biologists, and pharmacologists on drug discovery projects. --> Effectively summarised lab work, collecting, and complex quantitative data. --> Undertook regular poster presentations at both internal, national, and international meetings to a wide audience, ranging from industry professionals.

--> Published two first-author and 11 co-author peer-review articles.