Dr. Haresh Ajani

I am a skilled computational chemist with 9+ years of experience, including 5 years at Taros Chemical GmbH in the pharmaceutical industry. My expertise spans drug design, computational chemistry, database management, protein docking, chemoinformatics, ADME/T, quantum mechanics, and machine learning. I have a strong track record of collaborating with teams in drug discovery, identifying research needs, and proposing innovative solutions to advance pharmaceutical projects.

--> Designed and discovered novel inhibitors of RBBP4 and Kinases using SBDD, LBDD, and Cheminformatics methods. -->Developed and designed Structure-Based PROTAC Design computational method for PROTAC discovery using Protein-protein docking (Rosetta, Haddock, ICM). --> Designed and screened a Proteolysis Targeting Chimeras (PROTAC) library for protein degradation targets. --> Application of Structure-Based PROTAC Design computational method for hit identification, and lead optimization of PROTAC.

--> Coordinated the design of individual projects, providing ongoing mentoring support and collaborating with medicinal chemists, biologists, and pharmacologists on drug discovery projects. --> Effectively summarised lab work, collecting, and complex quantitative data. --> Undertook regular poster presentations at both internal, national, and international meetings to a wide audience, ranging from industry professionals.

--> Published two first-author and 11 co-author peer-review articles.