Dr. Holger Kubas

Angestellt, Head of Early Stage Development, Orals Development, Merck Group
Frankfurt, Germany

Fähigkeiten und Kenntnisse

Experienced in: drug discovery
medicinal chemistry
synthesis of small compounds and peptides
lead optimization
structure-activity-relationship
evaluation of early ADME & tox data (preclinical d
metabolite profiling
interdisciplinary teamwork
process chemistry (GMP
ICH)
scale-up
API impurity profiling
drug repurposing / repositioning
CRO management
IP protection / drafting of patent applications
presentation of scientific results
radiopharmaceutical chemistry
neurological disorders
cancer.

Werdegang

Berufserfahrung von Holger Kubas

  • Current 8 years and 8 months, since Oct 2017

    Head of Early Stage Development, Orals Development

    Merck Group
  • 3 years and 2 months, Aug 2014 - Sep 2017

    Principal Scientist / Manager Research Pharmaceutics

    Merck KGaA, Merck Serono

    Lab Head Chemical & Pharmaceutical Development, Research Pharmaceutics 5 Physico-chemical characterization of NCEs, analytical method development Early formulation development CMC and discovery project work

  • 1 year, Sep 2013 - Aug 2014

    External Expert NCE

    IADP e.V. / Merck KGaA

    Research Pharmaceutics Merck Serono Global Research & Early Development / CMC-D NCE Characterization Early Formulation Development

  • 3 years and 8 months, Jan 2010 - Aug 2013

    Scientific Expert Medicinal Chemistry

    Merz Pharmaceuticals GmbH

    Scientific Expert Medicinal Chemistry, Chemical R&D

  • 1 year and 5 months, Aug 2008 - Dec 2009

    Associate Scientific Expert Medicinal Chemistry

    Merz Pharmaceuticals GmbH

    Associate Scientific Expert Medicinal Chemistry, Chemical R&D

  • 1 year and 3 months, Jun 2007 - Aug 2008

    Research Scientist Radiopharmaceutical Chemistry

    German Cancer Research Center

    Postdoc, Department Radiopharmaceutical Chemistry

  • 3 years and 5 months, Jan 2004 - May 2007

    Ph.D. Student

    J. W. Goethe-University, Frankfurt am Main

    Ph.D. in Medicinal Chemistry

Ausbildung von Holger Kubas

  • Pharmacy

    J. W. Goethe-University Frankfurt/M., Germany

Sprachen

  • German

    C2 (Verhandlungssicher / Muttersprachlich)

  • English

    C1 (Fließend)

  • French

    A1-A2 (Grundkenntnisse)

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