Huiqiang Cai

Fähigkeiten und Kenntnisse

Model advanced prostate cancer in mice with AAV and CRISPR technolgy
Optimize Sleeping Beauty transgenic vectors for gene therapeutic use
Plasmid vector engineering for gene therapy use
DNA-barcoding patient-derived organoid cells
Human-induced pluripotent stem cells (iPSCs) culture and differentiation

Werdegang

Berufserfahrung von Huiqiang Cai

  • Bis heute 1 Jahr und 6 Monate, seit Feb. 2025

    Postdoctoral Scientist

    iiT Research & Development GmbH

  • 9 Monate, Juni 2024 - Feb. 2025

    Consultant

    IO Biotech

    Support for molecular engineering (mRNA vaccine constructs)

  • 2 Jahre, Feb. 2023 - Jan. 2025

    Postdoctoral Researcher

    University Hospital Essen

    Research tumor heterogeneity at single cell and spatial level, and Screen potential powerful medicine drugs. The main project was to Leverage already existing and newly generated patient-derived organoids, high-throughput sequencing methods, RNA-FISH and tracing technologies with novel DNA barcoding platforms, to unravel tumor cell autonomous as well as context-driven properties and functionally elucidate the dynamic plasticity of 3 cancer ecosystems. Transduction of organoids with retrovirus containing DNA

  • 4 Jahre, Jan. 2019 - Dez. 2022

    Postdoctoral Researcher

    Aarhus University

    Mimic the metastatic castration-resistant prostate cancer in mice by combining AAV-based delivery system with CRISPR/Cas9 technology.

  • 6 Monate, Juli 2018 - Dez. 2018

    Postdoctoral Researcher

    Max Delbrück Center for Molecular Medicine

    Optimize Sleeping Beauty transposon system for gene therapy application. Role of human endogenous retrovirus K in melanoma development. iPSCs differentiation to retinal epithelial cells.

Ausbildung von Huiqiang Cai

  • 2013 - 2018

    PhD

    Humboldt University of Berlin

    PhD projects were performed at the Max Delbrück Center for Molecular Medicine, Berlin. 3 independent projects: transposon-based transgene therapy; iPSC differentiation to retinal cells; role of human endogenous virus K in melanoma.

  • 2 Jahre und 10 Monate, Sep. 2009 - Juni 2012

    Master of Science - MS

    Donghua University

    Inferring the genetic structure of Chinese wild mice; Gene mapping of pubertal timing in mice

  • 3 Jahre und 10 Monate, Sep. 2005 - Juni 2009

    Bachelor of Science - BS

    Shanxi Agricultural University

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