Dr. Jérôme Clerc

Identification of MicroRNAs (miRNAs) Small Molecules Ligands using Biology-Oriented Synthesis - Combinatorial synthesis, continuous flow synthesis, development of cellular-based assay

Supervisor: Prof. Dr. Dr. h.c. Lutz F. Tietze. Total synthesis of the novel lignan linoxepin via a challenging palladium-catalyzed domino-reaction. Asymmetric copper(I)-catalyzed borylation.

Development and test of new furan derivatives for polymers stabilization applications

Palladium-catalyzed synthesis of heterocyclic active molecules using parallel synthetic method

Supervisor: Prof. Dr. Herbert Waldmann / Dr. Markus Kaiser. Total synthesis of natural products syringolin A and B and biological evaluation thereof. Structure-Activity-Relationship analysis and biochemical assay towards the inhibition of the proteasome system.

Molecular and supramolecular organic chemistry. 9-months-internship under the supervision of Dr. Frédéric Leroux and in collaboration with Lonza AG “Synthesis of new biaryl ligands for amination and Suzuki cross-coupling”

3-months internship at the University of Glasgow, Scotland, under the supervision of Prof. Dr. David J. Procter “Samarium(II)-mediated cyclization reactions of γ,δ–unsaturated ketones”