João Duarte

Angestellt, Researcher (FNS Ambizione fellow), Laboratory for Functional and Metabolic Imaging, EPFL
Lausanne, Switzerland

Fähigkeiten und Kenntnisse

metabolic regulation
diabetic encephalopathy
Alzheimer’s disease
biomarkers
neuromodulation
neuroprotection
neurodegeneration
magnetic resonance spectroscopy

Werdegang

Berufserfahrung von João Duarte

  • Current 12 years and 8 months, since Oct 2013

    Researcher (FNS Ambizione fellow)

    Laboratory for Functional and Metabolic Imaging, EPFL

    Investigation of brain energy metabolism and non-invasive biomarkers in diabetic encephalopathy.

  • 5 years, Oct 2008 - Sep 2013

    Researcher (Premier assistant)

    Dep. Radiology, Faculty of Biology and Medicine, University of Lausanne

    Enrolled in the study of energy metabolism in the rodent brain using in vivo 1H and 13C magnetic resonance spectroscopy (MRS) at high field, aiming at determining metabolic pathways that support glutamatergic and GABAergic neurotransmission and discovering neurochemical markers of brain dysfunction upon acute hypoglycaemia and redox dysregulation.

  • 1 year and 2 months, Sep 2007 - Oct 2008

    Exchange student

    LIFMET, EPFL.

    Determination of glucose transport kinetics and neurochemical profiles in vivo in the hippocampus of diabetes rat models using 1H MRS. Implementation of 13C MRS sequences at 9.4 T for in vivo studies.

  • 4 years, Oct 2004 - Sep 2008

    Graduate student

    Department of Biochemistry, Faculty of Science and Technology, UC

    Biochemical modifications in the hippocampus underlying memory impairment in insulin-resistant and insulin-dependent animal models of diabetes. Neuroprotective strategies for prevention of diabetes-induced hippocampal alterations.

  • 6 months, Jul 2005 - Dec 2005

    Exchange student

    LIFMET, EPFL

    Determination of glucose transport kinetics and neurochemical profiles in vivo in the hippocampus of diabetes rat models using 1H MRS. Implementation of 13C MRS sequences at 9.4 T for in vivo studies.

  • 1 year and 1 month, Sep 2003 - Sep 2004

    Undergraduate student, CNC, UC

    CNC, UC

Ausbildung von João Duarte

  • 4 years and 6 months, Sep 2004 - Feb 2009

    Biochemistry, Bioenergetics

    University of Coimbra

    Biochemical modifications in the hippocampus underlying memory impairment in insulin-resistant and insulin-dependent animal models of diabetes. Neuroprotective strategies for prevention of diabetes-induced hippocampal alterations.

  • 5 years and 1 month, Sep 1999 - Sep 2004

    Biochemistry

    University of Lisbon

    Modulation of hippocampal metabolism by adenosine receptors in hippocampal slices submitted to hypoxia and re-oxygenation. Effect of insulin-dependent diabetes and chronic hyperglycaemia on the adenosinergic neuromodulation system.

Sprachen

  • French

    B1-B2 (Gute Kenntnisse)

  • English

    C1 (Fließend)

  • Spanish

    B1-B2 (Gute Kenntnisse)

  • Portuguese

    C2 (Verhandlungssicher / Muttersprachlich)

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