Julien Da Silva

Research topic: divergent synthesis of PNA-encoded peptidic libraries targeting proteases and phosphatases. Use of solid phase synthesis, parallel synthesis techniques, automated and semi-automated peptide synthesis equipments

Research Associate in Medicinal Chemistry on the tyrosine kinase bcr-abl project. Synthesis of small molecule libraries (5-20 mg), scale-up of key intermediates (70g) and of final compounds (200-500 mg) for preliminary in vivo testing.