Kilian Brand

- Planning, direction, and coordination of activities concerned with design, construction, modification, and maintenance of equipment and machinery in industrial plant: Establishing standards and policies for pollution control, installation, modification, quality control, testing, operating procedure, inspection, and maintenance of equipment, according to engineering principles and safety regulations.

Biomanufacturing & Processing - Downstream processing for therapeutic monoclonal antibodies - Batch planning for purification of 200L fermenter broth - Execution, evaluation and documentation of experiments for protein purification: For example chromatographic separation, filtration, UF-DF, virus filtration - Analytical evaluation of the purification steps - Implementation of new technologies, for example, membrane chromatography, continuous purification strategies (Bio SMB) - Upscaling, Downscaling

Analytical Science - Analytical evaluation of proteins by HPLC and SEC - Method development for HPLC and SEC - Preparation and implementation of validation and robustness studies (validation plan, practical implementation, validation protocol) - Statistical test evaluation (Biost@t)

Process Engineering - Implementation and optimization of chemical syntheses in laboratory scale - Chemical process technology on a laboratory scale - Development and improvement of analytical methods

Quality Control - Conduct of release-relevant tests - GMP-compliant documentation of the test results - Validations and inspections - Investigation of OOS results and deviations

Wahlpflichtfächer: Prozessintensivierung, Biotechnologie

Fachoberschule in Abendform