Dr. Martin Göttle

Analytical Project Manager, Biologicals - GMP-relevant drug analytics according to SOPs - Timeline-sensitive management of analytical projects - Communication with analysts, customers and coworkers - Execution of experiments, data analysis, documentation, final reporting

Cell signaling by G protein-coupled receptors; In vitro cellular and non-cellular assays for the investigation of biomarkers associated with disease and cell signaling pathways in the CNS, heart and lung; Analytical chemistry; Development of analytical methods. Institute of Pharmacology, Hannover Medical School, Germany; Mentor: Prof. Dr. R. Seifert

Development of biochemical assays for the identification of protein targets and signaling networks associated with neurological disease; Engineering of cell models; Quantification of dopamine, serotonin and metabolites; Quantification of protein expression in samples from human and mouse brain; SILAC proteomics, HPLC-MS/MS metabolomics, transcriptomics, immunostaining, RT-PCR, fluorescence microscopy, FACS; Mentor: Prof. H. A. Jinnah, M.D., Ph.D.

Identification of Protein-Targets of Novel Second Messengers; Protein isolation from smooth muscle tissue with ligand-functionalized solid phases; Institute of Pharmacology, Regensburg University, Germany; Mentor: Prof. Dr. J. Schlossmann

Degree: With honors (Summa cum laude); Characterization of enzymatic activities of cell signaling enzymes in the CNS, the heart and bacterial toxins; Screening for fluorescent inhibitors and activators for purified protein targets; Investigation of ligand-target-interactions; Mentor: Prof. Dr. R. Seifert

Development of Biochemical Methods for the Determination of Affinity, Activity and Selectivity of New Ligands to G Protein-Coupled Receptors; Expression of serotonin receptors, histamine receptors in mammalian cells; Thesis + overall grade: "Very good" (1.4); Mentor: Prof. Dr. A. Buschauer

Surface coatings for biochips; Surface functionalization; Surface Chemistry; Physical Chemisty

Technological Chemistry

Surface chemistry; Surface coatings

Degree: With honors (Summa cum laude); Characterization of enzymatic activities of cell signaling enzymes in the CNS, the heart and bacterial toxins; Screening for fluorescent inhibitors and activators for purified proteins; Investigation of ligand-target-interactions; Mentor: Prof. Dr. R. Seifert

Development of Biochemical Methods for the Determination of Affinity, Activity and Selectivity of New Ligands to G Protein-Coupled Receptors; Expression of serotonin receptors, histamine receptors in mammalian cells; Thesis + overall grade: "Very good" (1.4); Mentor: Prof. Dr. A. Buschauer

Bachelor Thesis in Chemistry; Bachelor thesis and overall grade: "Very good" (1.0)