Dr. Martin Roßmanith

"Characterization and modulation of neuronal ensembles involved in reward learning" Prof. Dr. Rainer Spanagel's laboratory Institute of Psychopharmacology Central Institute of Mental Health - Molecular Biology and Neuroanatomy (35S-In situ Hybridization, Fluorescent In situ Hybridization - RNAscope, Immunohistochemistry, Daun02 silencing of neuronal ensembles) - Electrophysiology (Whole-cell patch clamp) - Behavioural neuroscience (Operant conditioning, Surgical procedures)

Master thesis: "Dopamine-transporter mutant rats: New Animal Model to assess behavioural and neurobiochemical disturbances caused by hyperdopaminergia" - Behavioural and cognition studies - Sterotaxic Surgery - Microdialysis - HPLC (Collaboration with AbbVie)

Laser vs. pinprick somatotopy coupled with EEG and MEG measurements in healthy control subjects

Preclinical study including active pharmaceutical ingredient tests

Generation of expression constructs into Adeno-Associated Virus (AAV) Cloning and Expression vectors

Bachelor thesis: "Determination of the half-life time of tetanus toxin light chain and tetanus toxon light chain variants" - Cell culture primary neurons - Western Blot - Gene Sequencing

Field studies and behavioural experiments examining hierachy and sexual behaviour of Physignathus lesueurii lesueurii

o EU-GMP-Leitfaden Teil 1-3 + Anhänge o ICH-Q10 o 21 CFR part 820 o AMWHV o PQS (SOPs, Documentation, CAPA, Change Management, Validation, Quality control, Audit...)

o European Union GCP regulations o German GCP laws (as described in AMG & MPG) o ICH-GCP Guidelines o Clinical trial design and conductance o Clinical data management o Quality management

- Molecular Biology and Neuroanatomy (35S-In situ Hybridization, Fluorescent In situ Hybridization - RNAscope, Immunohistochemistry, Daun02 silencing of neuronal ensembles) - Electrophysiology (Whole-cell patch clamp) - Behavioural neuroscience (Operant conditioning, Surgical procedures)

- In-depth insight into Neuroscience with strong emphasis on practice experience - Master thesis: "Dopamine-transporter mutant rats: New Animal Model to assess behavioural and neurobiochemical disturbances caused by hyperdopaminergia"

- Interdicipinary (Biology, Chemistry, Physics, Mathematics) - Molecular Biology, Microbiology, Physiology, Ecology, Developmental Biology, Marine Biology - Bachelor thesis: "Determination of the half-life time of tetanus toxin light chain and tetanus toxon light chain variants"